Alternating monocular adducting saccadic pulses and dissociated adducting nystagmus during lateral gazes in spinocerebellar ataxia type 3

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This study was supported by Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Education, Science and Technology (No. NRF-2016R1D1A1B04935568).

Author information




Dr. Lee analyzed and interpreted the data and wrote the manuscript. Drs. H.J. Kim, and Choi analyzed and interpreted the data, and revised the manuscript. Drs. J.S. Kim designed and conceptualized the study, interpreted the data, and revised the manuscript.

Corresponding author

Correspondence to Ji-Soo Kim.

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Conflicts of interest

Drs. S.U. Lee, H.J. Kim, and J.Y. Choi report no disclosures. Dr. J.S. Kim serves as an associate editor of Frontiers in Neuro-otology and on the editorial boards of the Journal of Clinical Neurology, Frontiers in Neuro-ophthalmology, Journal of Neuro-ophthalmology, Journal of Vestibular Research, Journal of Neurology, and Medicine.

Ethical approval

This study followed the tenets of the Declaration of Helsinki and was performed according to the guidelines of Institutional Review Board of Seoul National University Bundang Hospital (B-1906-549-701).

Electronic supplementary material

Below is the link to the electronic supplementary material.

Video 1 Exotropia is evident during alternating cover test (MP4 21470 kb)

Video 2 The patient shows alternating monocular adducting saccades in both eyes followed by glissadic eye movements (MP4 1768 kb)

Video 3 The patient shows a pulse-step mismatch, especially in the adducting eye, and dissociated adducting nystagmus during horizontal saccades. Vertical saccades are slow in both directions and show a pulse-step mismatch upward (MP4 42619 kb)

Supplementary material 1 (DOCX 34 kb)

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Lee, SU., Kim, HJ., Choi, JY. et al. Alternating monocular adducting saccadic pulses and dissociated adducting nystagmus during lateral gazes in spinocerebellar ataxia type 3. J Neurol 267, 279–281 (2020).

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