Aperiodic alternating nystagmus in isolated vestibular nucleus infarction
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In patients with an acute vestibular syndrome, it is sometimes challenging to make a differential diagnosis between acute peripheral vestibulopathy (APV) and central vestibular disorders . Isolated acute vertigo has been reported in a tiny infarct involving caudal cerebellum [2, 3, 4, 5] or vestibular nucleus (VN) [6, 7]. Patients with isolated VN infarction mostly presented with combined clinical features of peripheral and central vestibulopathy [6, 7]. However, aperiodic alternating nystagmus has not been described in isolated VN infarction. We report a patient with isolated VN infarction who initially presented with clinical manifestations of APV, and subsequently developed aperiodic alternating nystagmus.
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Conflicts of interest
We have no disclosure of any competing interest.
Ethical approval for research involving human participants and/or animals
All experiments followed the tenets of the Declaration of Helsinki, and this study was approved by the institutional review board.