Skip to main content

Advertisement

SpringerLink
Log in

High incidence of carpal tunnel syndrome after deep brain stimulation in Parkinson’s disease

  • Original Communication
  • Published:
Journal of Neurology Aims and scope Submit manuscript

Abstract

We observed several cases of carpal tunnel syndrome (CTS) revealed after subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson’s disease (PD). 115 consecutive PD patients who underwent STN-DBS between 2010 and 2014 at the Neurological Hospital in Lyon were retrospectively included. CTS was accepted as the diagnosis only if clinical examination and ENMG both confirmed it. Nine patients (7.8 %) developed CTS in the 2 years following surgery, which is far beyond the 2.7/1000 incidence in the general population. The present study shows an overrepresentation of CTS occurrence after STN-DBS in PD.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. Tuppin P, Blotière P-O, Weill A, Ricordeau P, Allemand H (2011) Carpal tunnel syndrome surgery in France in 2008: patients’ characteristics and management. Rev Neurol (Paris) 167(12):905–915

    Article  CAS  Google Scholar 

  2. Yucel A, Yilmaz O, Babaoglu S, Acar M, Degirmenci B (2008) Sonographic findings of the median nerve and prevalence of carpal tunnel syndrome in patients with Parkinson’s disease. Eur J Radiol 67(3):546–550

    Article  PubMed  Google Scholar 

  3. American Association of Electrodiagnostic medicine (1999) Guidelines in electrodiagnostic medicine. Practice parameter for electrodiagnostic studies in carpal tunnel syndrome. Muscle Nerve Suppl 8:S141–S167

    Google Scholar 

  4. Nordstrom DL, DeStefano F, Vierkant RA, Layde PM (1998) Incidence of diagnosed carpal tunnel syndrome in a general population. Epidemiology 9:342–345

    Article  CAS  PubMed  Google Scholar 

  5. Mondelli M, Giannini F, Giacchi M (2002) Carpal tunnel syndrome incidence in a general population. Neurology 58:289–294

    Article  PubMed  Google Scholar 

  6. Latinovic R, Gullifors MC, Hughes RAC (2006) Incidence of common compressive neuropathies in primary care. J Neurol Neurosurg Psychiatry 77(2):263–265

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Kimber T, Antonini A (2016) Peripheral neuropathy and levodopa therapy in Parkinson disease: novel insights. Eur J Neurol 23(3):435–436

    Article  CAS  PubMed  Google Scholar 

  8. Comi C, Magistrelli L, Oggioni GD, Carecchio M, Fleetwood T, Cantello R, Mancini F, Antonini A (2014) Peripheral nervous system involvement in Parkinson’s disease: evidence and controversies. Parkinsonism Relat Disord 20(12):1329–1334

    Article  CAS  PubMed  Google Scholar 

  9. Yang SN, Kang HJ, Yoon JS, Won SJ, Seo W-K, Koh SB (2014) Is median nerve enlargement at the wrist associated with tremor in Parkinson disease? J Ultrasound Med Off J Am Inst Ultrasound Med 33(12):2079–2083

    Google Scholar 

  10. Han SW, Cheon KY, Kim JY, Baik JS (2015) Carpal tunnel syndrome in patients with tremor dominant parkinson’s disease. PloS One 10(6):e0130779. doi:10.1371/journal.pone.0130779

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Acknowledgments

We wish to thank Mrs P. Thobois-Maillot for English revision.

Author information

Authors and Affiliations

  1. Service de Neurologie C, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, 69000, Lyon, France

    Marine Loizon, Chloé Laurencin, Teodor Danaila & Stéphane Thobois

  2. Service d’Electroneuromyographie, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, 69000, Lyon, France

    Christophe Vial

  3. CNRS, Centre de Neurosciences Cognitives, UMR 5229, 69500, Bron, France

    Chloé Laurencin, Teodor Danaila & Stéphane Thobois

  4. Faculté de médecine Lyon Sud Charles Mérieux, Université de Lyon, Université Lyon 1, 69000, Lyon, France

    Chloé Laurencin & Stéphane Thobois

Authors
  1. Marine Loizon
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Chloé Laurencin
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Christophe Vial
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Teodor Danaila
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Stéphane Thobois
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Chloé Laurencin.

Ethics declarations

Ethical standards

All patients gave their informed consent prior to their inclusion in the study.

Conflicts of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

Additional information

Marine Loizon and Chloé Laurencin are co-first authors.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Loizon, M., Laurencin, C., Vial, C. et al. High incidence of carpal tunnel syndrome after deep brain stimulation in Parkinson’s disease. J Neurol 263, 2416–2418 (2016). https://doi.org/10.1007/s00415-016-8279-9

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00415-016-8279-9

Keywords

Search

Navigation