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Table 4 Correlations between clinical/MRI multiple sclerosis disease variables and work productivity

From: Brain MRI lesions and atrophy are associated with employment status in patients with multiple sclerosis

Variables Patient characteristics (years) Physical disability Work Productivity and Activity Impairment-General Health (%) Brain volume measures
Age Disease duration EDSS Activity impairment Overall work impairment Absenteeism Presenteeism BPV T1 lesion volume T2 lesion volume T1/T2 lesion volume ratio
BPV −0.370* −0.199* −0.219* −0.150 −0.112 −0.018 −0.132 – −0.337* −0.381* −0.198*
T1 hypointense lesion volume −0.008 0.147 0.326* 0.157 0.116 0.021 0.138 −0.337* – 0.869* 0.366*
T2 hyperintense lesion volume −0.016 0.226* 0.186 0.116 0.062 −0.028 0.090 −0.381* 0.869* – 0.098
T1/T2 lesion volume ratio 0.173 0.045 0.331* 0.055 0.121 0.147 0.122 −0.198* 0.366* 0.098 –
Baseline EDSS 0.273* 0.286* – 0.424* 0.195 −0.062 0.211 −0.219* 0.326* 0.186 0.331*
Age at MRI – 0.374* 0.273* 0.153 −0.015 −0.162 0.123 −0.370* −0.008 −0.016 0.173
Disease duration 0.374* – 0.286* 0.197 0.118 −0.039 0.170 −0.199* 0.147 0.226* 0.045
  1. All correlations are Pearson, except for those involving EDSS which are Spearman; Asterisks indicate p value <0.05
  2. BPV brain parenchymal volume, EDSS expanded disability status scale score
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