Journal of Neurology

, 258:339 | Cite as

Treatment of dysautonomia in extrapyramidal disorders

  • Tjalf Ziemssen
  • Gerd Fuchs
  • Wolfgang Greulich
  • Heinz Reichmann
  • Michael Schwarz
  • Birgit Herting


Although extrapyramidal diseases are commonly thought to solely affect the (extrapyramidal) motor system, non-motor symptoms such as behavioural abnormalities, dysautonomia, sleep disturbances and sensory dysfunctions are also frequently observed. Autonomic dysfunction is an important clinical component of extrapyramidal disease, but it is often not formally assessed, and thus frequently misdiagnosed. Symptoms of autonomic dysfunction can impact more on quality of life than motor symptoms. Appropriate symptom-oriented diagnosis and symptomatic treatment as part of an interdisciplinary approach can greatly benefit the patient. This review elaborates a limited overview on the treatment of cardiovascular, gastrointestinal, urogenital and sudomotor autonomic dysfunction in various extrapyramidal syndromes.


Extrapyramidal disease Parkinson’s disease Autonomic dysfunction Multiple system atrophy Treatment Dysautonomia 


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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Tjalf Ziemssen
    • 1
  • Gerd Fuchs
    • 2
  • Wolfgang Greulich
    • 3
  • Heinz Reichmann
    • 4
  • Michael Schwarz
    • 5
  • Birgit Herting
    • 4
    • 6
  1. 1.Autonomic and neuroendocrinological laboratory, Department of NeurologyUniversity Clinic Carl Gustav Carus, Dresden University of TechnologyDresdenGermany
  2. 2.Parkinson ClinicWolfachGermany
  3. 3.Neurological clinicHELIOS clinic Hagen-Ambrock, University Witten/HerdeckeHagenGermany
  4. 4.Movement Disorders Research Group, Department of NeurologyUniversity Clinic Carl Gustav Carus, Dresden University of TechnologyDresdenGermany
  5. 5.Neurological ClinicDortmundGermany
  6. 6.Neurological clinicDiakonie hospitalSchwaebisch HallGermany

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