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Late-onset cardiac arrhythmia associated with vagus nerve stimulation

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References

  1. Ali II, Pirzada NA, Kanjwal Y, Wannamaker B, Medhkour A, Koltz MT, Vaughn BV (2004) Complete heart block with ventricular asystole during left vagus nerve stimulation for epilepsy. Epilepsy Behav 5:768–771. doi:10.1016/j.yebeh.2004.05.008

    Article  PubMed  Google Scholar 

  2. Amark P, Stodberg T, Wallstedt L (2007) Late onset bradyarrhythmia during vagus nerve stimulation. Epilepsia 48:1023–1025. doi:10.1111/j.1528-1167.2007.01023.x

    Article  PubMed  Google Scholar 

  3. Andriola MR, Rosenweig T, Vlay S (2000) Vagus nerve stimulator (VNS): introduction of asystole during implantation with subsequent successful stimulation. Epilepsia 41(s7):223. doi:10.1016/S0920-1211(00)00147-9

    Google Scholar 

  4. Annegers JF, Coan SP, Hauser WA, Leestma J (2000) Epilepsy, vagal nerve stimulation by the NCP system, all-cause mortality, and sudden, unexpected, unexplained death. Epilepsia 41:549–553. doi:10.1111/j.1528-1157.2000.tb00208.x

    Article  PubMed  CAS  Google Scholar 

  5. Ardesch JJ, Buschman HPJ, van der Burgh PH, Wagener-Schimmel JJC, van der Aab HE, Hagemana G (2007) Cardiac responses of vagus nerve stimulation: intraoperative bradycardia and subsequent chronic stimulation. Clin Neurol Neurosurg 109:849–852. doi:10.1016/j.clineuro.2007.07.024

    Article  PubMed  CAS  Google Scholar 

  6. Asconape JJ, Moore DD, Zipes DP, Hartman LM, Duffell WH (1999) Bradycardia and asystole with the use of vagus nerve stimulation for the treatment of epilepsy: a rare complication of intraoperative device testing. Epilepsia 40:1452–1454. doi:10.1111/j.1528-1157.1999.tb02019.x

    Article  PubMed  CAS  Google Scholar 

  7. Frei MG, Osorio I (2001) Left vagus nerve stimulation with the neurocybernetic prosthesis has complex effects on heart rate and on its variability in humans. Epilepsia 42:1007–1016. doi:10.1046/j.1528-1157.2001.0420081007.x

    Article  PubMed  CAS  Google Scholar 

  8. Galli R, Limbruno U, Pizzanelli C, Giorni FS, Lutzemberger L, Strata G, Pataleo L, Mariani M, Iudice A, Murri L (2003) Analysis of RR variability in drug-resistant epilepsy patients chronically treated with vagus nerve stimulation. Auton Neurosci 107:52–59. doi:10.1016/S1566-0702(03)00081-X

    Article  PubMed  Google Scholar 

  9. Iriarte J, Urrestarazu E, Alegre M, Macías A, Gómez A, Amaro P, Artieda J, Viteri C (2009) Late-onset periodic asystolia during vagus nerve stimulation. Epilepsia 50:928–932

    Article  PubMed  Google Scholar 

  10. Koenig SA, Longin E, Bell N, Reinhard J, Gerstner T (2008) Vagus nerve stimulation improves severely impaired heart rate variability in a patient with Lennox-Gastaut-Syndrome. Seizure 17:469–472. doi:10.1016/j.seizure.2007.11.004

    Article  PubMed  Google Scholar 

  11. Ronkainen E, Korpelainen JT, Heikkinen E, Myllylä VV, Huikuri HV, Isojärvi JIT (2006) Cardiac autonomic control in patients with refractory epilepsy before and during vagus nerve stimulation treatment: a one-year follow-up study. Epilepsia 47:556–562. doi:10.1111/j.1528-1167.2006.00467.x

    Article  PubMed  Google Scholar 

  12. Srinivasan B, Awasthi A (2004) Transient atrial fibrillation after the implantation of a vagus nerve stimulator. Epilepsia 45:1645. doi:10.1111/j.0013-9580.2004.31004.x

    Article  PubMed  Google Scholar 

  13. Stemper B, Devinsky O, Haendl T, Welsch G, Hilz MJ (2008) Effects of vagus nerve stimulation on cardiovascular regulation in patients with epilepsy. Acta Neurol Scand 117:231–236. doi:10.1111/j.1600-0404.2007.00944.x

    Article  PubMed  CAS  Google Scholar 

  14. Tatum WO, Moore DB, Stecker MM, Baltuch GH, French J, Ferreira J (1999) Ventricular asystole during vagus nerve stimulation for epilepsy in humans. Neurology 52:1267–1269

    PubMed  Google Scholar 

  15. Zaaimi B, Grebe R, Berquin P, Wallois F (2007) Vagus nerve stimulation therapy induces changes in heart rate of children during sleep. Epilepsia 48:923–930

    Article  PubMed  Google Scholar 

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Correspondence to Peter Borusiak.

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Borusiak, P., Zilbauer, M., Cagnoli, S. et al. Late-onset cardiac arrhythmia associated with vagus nerve stimulation. J Neurol 256, 1578–1580 (2009). https://doi.org/10.1007/s00415-009-5162-y

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  • DOI: https://doi.org/10.1007/s00415-009-5162-y

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