Abstract
We report a patient who has a tremor and unilateral ptosis and mydriasis without extraocular muscle paresis from an intra-axial lesion demonstrated on neuroimaging. Previously extraocular muscles sparing partial third nerve palsy has been thought to be due to extra-axial lesion such as vascular compression. Compared to proposed models for arrangement of oculomotor fascicle, this case demonstrates that it is possible to damage the fibers destined for levator and pupillomotor function without affecting the extra-ocular muscles.
References
Abdollah A, Francis GS (1990) Intraaxial divisional oculomotor nerve paresis suggests intraaxial fascicular organization. [comment]. Ann Neurol 28:589–590
Albayram S, Ozer H, Sarici A, Murphy K, Miller N (2006) Unilateral mydriasis without ophthalmoplegia – a sign of neurovascular compression? Case report. Neurosurgery 58:E582–E583 discussion E582–583
Breen LA, Hopf HC, Farris BK, Gutmann L (1991) Pupil-sparing oculomotor nerve palsy due to midbrain infarction. Arch Neurol 48:105–106
Castro O, Johnson LN, Mamourian AC (1990) Isolated inferior oblique paresis from brain-stem infarction. Perspective on oculomotor fascicular organization in the ventral midbrain tegmentum. Arch Neurol 47:235–237
Daroff RB (1971) Oculomotor manifestation of brainstem and cerebellar dysfunction. In: Smith JL (ed) Neuro-ophthalmology: symposium of the University of Miami and Bascom-Palmer Eye Institute. Huffman, Hallandale, pp 104–121
Ksiazek SM, Slamovits TL, Rosen CE, Burde RM, Parisi F (1994) Fascicular arrangement in partial oculomotor paresis. Am J Ophthalmol 118:97–103
Liu GT, Crenner CW, Logigian EL, Charness ME, Samuels MA (1992) Midbrain syndromes of Benedikt, Claude, and Nothnagel: setting the record straight. Neurology 42:1820–1822
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Chen, L., MacLaurin, W. & Gerraty, R.P. Isolated unilateral ptosis and mydriasis from ventral midbrain infarction. J Neurol 256, 1164–1165 (2009). https://doi.org/10.1007/s00415-009-5054-1
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00415-009-5054-1