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Sudden death due to auto-immune Addison’s disease in a 12-year-old girl

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Abstract

A 12-year-old female suffering from adreno-cortical insufficiency showed symptoms similar to a gastro-enteritis, and severe electrolytic and acid/base disturbances which progressed into cerebral oedema and death. Autopsy findings included depletion of the adrenal cortex, with enlargement and eosinophilia of surviving cells. In ante-mortem blood, anti-adrenal auto-antibodies were found and elevated levels of ACTH and cortisol with a low level of aldosterone.

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Authors and Affiliations

  1. Forensic Medicine Unit, University of Edinburgh Medical School, Teviot Place, Edinburgh EH8 9AG, Scotland, , , , , , GB

    A. M. Al Sabri & A. Busuttil

  2. Paediatric Pathology, Royal Hospital for Sick Children, Edinburgh, Scotland, , , , , , GB

    N. Smith

Authors
  1. A. M. Al Sabri
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  2. N. Smith
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  3. A. Busuttil
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Received: 14 November 1996 / Received in revised form: 2 April 1997

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Al Sabri, A., Smith, N. & Busuttil, A. Sudden death due to auto-immune Addison’s disease in a 12-year-old girl. Int J Leg Med 110, 278–280 (1997). https://doi.org/10.1007/s004140050085

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  • DOI: https://doi.org/10.1007/s004140050085

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