Abstract
The Y chromosome STRs DYS437, DYS438 and DYS439 were selected from publicly available genome databases and used to analyse an Italian population sample. A tetraplex PCR reaction including the highly informative DYS385 locus, was set up and used for the analysis of 131 male samples to determine allele frequencies and STR diversity values. The number of different haplotypes and the haplotype diversity value found from the analysis of the STRs included in the tetraplex reaction were very similar to those found from the analysis of the basic set of 7 Y-STRs (DYS19, DYS389I/II, DYS390, DYS391, DYS392 and DYS393) previously carried out on the same population sample. By combining the allelic states of the 11 Y-chromosomal STRs we could construct highly informative haplotypes that allowed the discrimination of 93.8% (120 out of 128) of the samples tested. This approach represents a very powerful tool for individual identification and paternity testing in forensic medicine.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received: 29 November 1999 / Accepted: 17 March 2000
Rights and permissions
About this article
Cite this article
Grignani, P., Peloso, G., Fattorini, P. et al. Highly informative Y-chromosomal haplotypes by the addition of three new STRs DYS437, DYS438 and DYS439. Int J Leg Med 114, 125–129 (2000). https://doi.org/10.1007/s004140000153
Issue Date:
DOI: https://doi.org/10.1007/s004140000153