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Molecular characterization of 23 Y chromosomal STR markers in the Gurjar population of National Capital Region (NCR), India

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Abstract

In the present study, DNA samples of 202 unrelated male individuals of Gurjar population were evaluated for the molecular diversity at 23 Y chromosomal Y-STR markers. Out of selected individuals, results showed 143 unique haplotypes. Highest degree of gene diversity (GD), polymorphic information content (PIC), and power of discrimination (PD) was observed as 0.7941, 0.7590, and 0.7902, respectively, for the locus DYS385a/b. Haplotype diversity (HD), gene diversity (GD), polymorphic information content (PIC), and power of discrimination (PD) was found to be 0.7079, 0.999999999989, 0.9999999996, and 0.999999999986, respectively, for the studied 23 Y-STR markers. Allele 11 of locus DYS392 was found to be the most frequent allele with the frequency of 0.762. In inter-population relationship, studied population showed genetic relatedness with the population of Jammu and Kashmir, India, and Ladakh, India. The haplotype data of the present study will not only enrich the existing Indian Y-STR data but will also be useful for forensic DNA application.

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Acknowledgements

The authors thankfully acknowledge Promega (India) for providing the multiplex STR kits used in the study.

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Correspondence to Pankaj Shrivastava.

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Ethical approval

The study was approved by the Institute Ethics Committee (Human Studies) of Maharani Laxmi Bai Medical College, Jhansi, UP, India, vide letter no. 4648 dated 05.09.2020.

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The authors declare no competing interests.

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Kapil Dev, R. K. Kumawat, and Pankaj Shrivastava have equal credentials

Supplementary Information

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Figure S1: Geographical distribution of the studied population. (JPG 78 KB)

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Figure S2: Principal Coordinate Analysis (PCoA) plot based on pairwise Rst values between studied population and compared populations from YHRD. (JPG 114 KB)

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Figure S3: NJ tree based on pairwise Fst values between studied population and compared populations generated after output of YHRD analysis (JPG 94 KB)

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Figure S4: Heat map based on pairwise Fst values between studied population and compared populations generated after output of YHRD analysis (JPG 134 KB)

Supplementary file5 (XLSX 35 KB)

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Dev, K., Kesharwani, L., Kushwaha, P. et al. Molecular characterization of 23 Y chromosomal STR markers in the Gurjar population of National Capital Region (NCR), India. Int J Legal Med 136, 555–556 (2022). https://doi.org/10.1007/s00414-021-02623-x

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  • DOI: https://doi.org/10.1007/s00414-021-02623-x

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