Skip to main content

Population genetic data for 21 autosomal STR loci in the Azerbaijani population using the Globalfiler™ kit

Abstract

The Republic of Azerbaijan is located in the southern Caucasus mountains, a region which is linguistically and ethnically diverse. We report allele frequency data for 21 autosomal loci from the Globalfiler™ kit in the Azerbaijani population using 467 individuals from Baku. Exact tests for Hardy Weinberg Equilibrium and Linkage Equilibrium were conducted, and all forensic parameters were estimated. High levels of Expected Heterozygosity HE were seen, with a minimum of 0.637 for TPOX and a maximum of 0.949 for SE33. Polymorphism Information Content (PIC) values for all STR loci were high, ranging from 0.587 for TPOX to 0.947 for SE33. Matching probability (MP) estimates ranged from 0.006 for SE33 to 0.178 for TPOX. Power of Discrimination (PD) values for most of the tested loci (17/21) were ≥ 0.9. The Combined Matching Probability (CMP) and the Combined Power of Discrimination (CPD) for all 21 loci were 7.84 × 10–27 and 1.0 respectively. Exact tests for population differentiation using all available Globalfiler™ datasets from across Europe and Asia reveal a general trend of higher differentiation with increasing geographical separation, but there is a need for additional population data from neighboring regions of Azerbaijan.

This is a preview of subscription content, access via your institution.

Data availability

Data available on request.

Code availability

N/A.

References

  1. 1.

    Yunusbayev B, Metspalu M, Metspalu E, Valeev A, Litvinov S, Valiev R, Akhmetova V, Balanovska E, Balanovsky O, Turdikulova S, Dalimova D, Nymadawa P, Bahmanimehr A, Sahakyan H, Tambets K, Fedorova S, Barashkov N, Khidiyatova I, Mihailov E, Khusainova R, Damba L, Derenko M, Malyarchuk B, Osipova L, Voevoda M, Yepiskoposyan L, Kivisild T, Khusnutdinova E, Villems R (2015) The genetic legacy of the expansion of Turkic-speaking nomads across Eurasia. PLoS Genet 11(4):e1005068

    Article  Google Scholar 

  2. 2.

    Samadov A (2019) Population of Azerbaijan | The State Statistical Committee of the Republic of Azerbaijan. [online] The State Statistical Committee of the Republic of Azerbaijan. Available at: https://www.stat.gov.az/source/demoqraphy/ap/?lang=en. (Accessed 27 Dec 2020)

  3. 3.

    Nasibov E, Bulbul O, Jabrayili G, Zorlu T, Shahzad M, Cengiz S, Filoglu G, Altuncul H, Sadixov G (2013) Allele frequencies of 15 STR loci in Azerbaijan population. Forensic Sci Int Genet 7(3):e99–e100

    CAS  Article  Google Scholar 

  4. 4.

    Mammadov ER, Mustafayev NS, Mammadov AC, Hasanov AB, Huseynova IM (2020) Population-genetic and comparative interpopulation studies of Azerbaijan population based on 15 autosomal STR markers. Gene 144804

  5. 5.

    Hares D (2012) Expanding the CODIS core loci in the United States. Forensic Sci Int Genet 6(1):e52–e54

    CAS  Article  Google Scholar 

  6. 6.

    Ristow P, D’Amato M (2017) Forensic statistics analysis toolbox (FORSTAT): a streamlined workflow for forensic statistics. Forensic Science International: Genetics Supplement Series 6:e52–e54

    Google Scholar 

  7. 7.

    Raymond M, Rousset F (1995) GENEPOP (Version 1.2): Population genetics software for exact tests and ecumenicism. J Heredity 86(3):248–249

  8. 8.

    Excoffier L, Lischer H (2010) Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Molec Ecol Resour 10(3):564–567

  9. 9.

    Nasidze I, Stoneking M (2001) Mitochondrial DNA variation and language replacements in the Caucasus. Proc Royal Soc London. Ser B: Biol Sci 268(1472):1197–1206

  10. 10.

    Nasidze I, Sarkisian T, Kerimov A, Stoneking M (2003) Testing hypotheses of language replacement in the Caucasus: evidence from the Y-chromosome. Hum Genet 112(3):255–261

    Article  Google Scholar 

Download references

Acknowledgements

We are very grateful to all participants in this study. We would also like to thank Dr. Bayram Bayramov, Zumrud Safarzadeh, and Jale Nasibova for laboratory assistance at the Genetics Resources Institute in Baku.

Funding

Laboratory consumables were purchased using funds from the Forensic Science Initiative and the Graduate Student Association at the University at Albany.

Author information

Affiliations

Authors

Corresponding author

Correspondence to Arati Iyengar.

Ethics declarations

Ethics approval

Approval granted by the Institutional Review Board (IRB) at the University at Albany (No.19E050).

Consent to participate

All participants provided informed consent.

Conflict of interest

The authors declare no competing interests.

Additional information

Publisher's note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (XLSX 22 KB)

Supplementary file2 (DOCX 31 KB)

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Aliyeva, A., Gellatly, V., Abbasov, M. et al. Population genetic data for 21 autosomal STR loci in the Azerbaijani population using the Globalfiler™ kit. Int J Legal Med 135, 1789–1791 (2021). https://doi.org/10.1007/s00414-021-02610-2

Download citation

Keywords

  • Population database
  • STRs
  • Human identification
  • Caucasus
  • Forensic DNA profiling