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Genetic polymorphism investigation of 16 X-STR loci in the Bai ethnic minority in Yunnan Province, Southwest China

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Abstract

To investigate the genetic variation and forensic efficiency of 16 X-chromosomal short tandem repeat (X-STR) loci (DX6795, DXS9902, DXS8378, HPRTB, GATA165B12, DXS7132, DXS7424, DXS6807, DXS6803, GATA172D05, DXS6800, DXS10134, GATA31E08, DXS10159, DXS6789, and DXS6810) in the Bai minority, we calculated allele frequencies, forensic parameters, and haplotype frequencies in 424 (202 males and 222 females) unrelated, healthy Bai individuals from Dali Bai Autonomous Prefecture in Yunnan Province, China. We observed a total of 132 alleles; 5–19 alleles were detected in each locus, and the corresponding allele frequencies ranged from 0.0016 to 0.7589. All of the loci detected were highly polymorphic in the Bai population in Yunnan Province, except DXS6800. The values for the combined power of discrimination in females (PDf) and males (PDm) were 0.999999999999996 and 0.999999997487061, respectively. According to a phylogenetic tree, neighboring populations and different nationalities in the same area appeared to have relatively close evolutionary relationships. This study provides and complements X-chromosome genetic polymorphism data for the Bai people in Yunnan Province, Southwest China, and enriches the available reference materials for this Chinese minority population.

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Acknowledgments

This work was supported by grants from the National Natural Science Foundation of China (grant numbers 81860258 and 31860300), the Joint Special Funds for the Department of Science and Technology of Yunnan Province-Kunming Medical University (grant numbers 2017FE467(-022), 2018FE001(-131), and 2019FE001(-011)), the Yunnan Educational Science Foundation program (grant numbers 2018JS170 and 2018JS171), the Yunnan Provincial Young Academic and Technical Leader Reserve Talent Project (grant number 2018HB104), the Hundred-Talent Program of Kunming Medical University (grant number 60117190447), and the Science and Technology Innovation Group of Kunming Medical University (grant number CXTD201803). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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Author notes

  1. Lili Qing and Yi Li contributed equally to this work.

Authors and Affiliations

  1. School of Forensic Medicine, Kunming Medical University, Kunming, 650500, Yunnan Province, People’s Republic of China

    Lili Qing, Linlin Liu, Dengyong Chen, Xiufeng Zhang, Shengjie Nie & Liping Hu

  2. Dali Public Security Bureau, Dali, Yunnan Province, People’s Republic of China

    Yi Li & Jianli Han

  3. Dali Bai Autonomous Prefecture Public Security Judicial Expertise Center, Dali, Yunnan Province, People’s Republic of China

    Yuchao Shi

  4. Judicial Expertise Center, Kunming Medical University, Kunming, Yunnan Province, People’s Republic of China

    Renwu Huang, Xiufeng Zhang, Shengjie Nie & Liping Hu

Authors
  1. Lili Qing
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  2. Yi Li
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  3. Linlin Liu
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  4. Dengyong Chen
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  5. Jianli Han
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  6. Yuchao Shi
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  7. Renwu Huang
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  8. Xiufeng Zhang
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  9. Shengjie Nie
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  10. Liping Hu
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Corresponding authors

Correspondence to Xiufeng Zhang, Shengjie Nie or Liping Hu.

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The authors declare that they have no conflict of interest.

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Approval was obtained from the ethics committee of Kunming Medical University. The procedures used in this study adhere to the tenets of the Declaration of Helsinki.

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Qing, L., Li, Y., Liu, L. et al. Genetic polymorphism investigation of 16 X-STR loci in the Bai ethnic minority in Yunnan Province, Southwest China. Int J Legal Med 136, 543–545 (2022). https://doi.org/10.1007/s00414-020-02454-2

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  • DOI: https://doi.org/10.1007/s00414-020-02454-2

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