Abstract
Genetic diversity indices and forensic parameters at 20 autosomal short tandem repeat (STR) loci were evaluated in 541 unrelated individuals of north-western Indian state Rajasthan. In total, 243 alleles were observed with an average of 12.15 alleles per locus. The most polymorphic and discriminative locus was Penta E with a value of 0.908 and 0.984, respectively. The combined power of exclusion and the combined power of discrimination were found to be 0.999999998 and 1, respectively. Additionally, the genetic relationship of the studied population with the reported Indian as well as global populations was investigated. The studied population showed genetic affinity with the previously reported population of Rajasthan and geographical close population’s, i.e., populations of Uttar Pradesh, Madhya Pradesh, and Jharkhand. All the STR loci were found polymorphic, and the select panel of STRs was found suitable for population genetic studies and forensic analysis.
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Acknowledgments
Authors are thankful to the Director, State Forensic Science Laboratory, Jaipur, Rajasthan, India, for support and encouragement for undertaking this study.
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RK and RK (Kumawat) designed the study, RK (Kumawat) and AT analyzed the samples, RK did the quality check and statistical analysis. RK and RK (Kumawat) wrote the manuscript. AK and AT reviewed the manuscript. All authors read and approved the final manuscript.
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Rajesh Kumar, Anand Kumar, and R. K. Kumawat are authors with equal credential
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Fig. S1
Geographic location of studied population (JPG 46 kb).
Fig. S2
NJ tree comparison based on Fst genetic distance calculated from autosomal STRs (JPG 116 kb).
Fig. S3
PCA plot comparison based on Fst genetic distance calculated from autosomal STRs (JPG 88 kb).
Table S1
Allele frequencies of north-western Indian population (n=541) (XLSX 13 kb).
Table S2
Forensic parameters of north-western Indian population (n=541) (XLSX 11 kb).
Table S3
Nei's Da distance matrix between studied and compared populations (XLSX 9 kb).
Table S4
Population data used for analysis of genetic distances by using NJ tree and PCA plot. (XLSX 11 kb).
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Kumar, R., Kumar, A., Kumawat, R.K. et al. Genomic polymorphism in North-western Indian population based on autosomal STR’s: a population data study. Int J Legal Med 135, 765–766 (2021). https://doi.org/10.1007/s00414-020-02330-z
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DOI: https://doi.org/10.1007/s00414-020-02330-z