Genetic diversity and phylogenetic analysis of 29 Y-STR loci in the Tibetan population from Sichuan Province, Southwest China


Y-Chromosomal short tandem repeat polymorphisms (Y-STRs) are widely applied in human forensic cases and population genetic studies. There is a lack of information about the Sichuan Tibetan population in the Y-STR Haplotype Reference Database (YHRD,, release 59). In this study, 502 unrelated male individuals residing in the Sichuan Province were recruited and genotyped at 29 Y-STR loci. A total of 479 haplotypes were observed, 460 (96.03%) of which were unique. The haplotype diversity (HD) and discrimination capacity (DC) for the Sichuan Tibetan population were 0.9998 and 0.9542, respectively. To reveal the genetic diversities and relationships between the Chinese Sichuan Tibetan and 29 other previously reported populations, forensic parameter analysis, multi-dimensional scaling, and phylogenetic reconstruction were performed. The results showed that the Sichuan Tibetan population was relatively isolated from other populations, suggesting that genetic proximity is in line with geographical boundaries.

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The authors thank the voluntary participants in this study.


This study was supported by the National Natural Science Foundation of China (NSFC, No. 81772030, and 81701866), the Postdoctoral Fund of Sichuan University (No.2017SCU12049), and the Outstanding Youth Fund of Sichuan University (No. 2016SCU04A07).

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Correspondence to Haibo Luo.

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The study was approved by the Ethics Committee of Sichuan University and a written informed consent letter was obtained from each participant.

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Song, F., Xie, M., Xie, B. et al. Genetic diversity and phylogenetic analysis of 29 Y-STR loci in the Tibetan population from Sichuan Province, Southwest China. Int J Legal Med 134, 513–516 (2020).

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  • Tibetan population
  • Y-STR
  • Haplotypes
  • Population genetic analysis