Genetic diversities and phylogenetic analysis of 18 autosomal STR loci in the Uyghur population living in Ili, Northwest China

26 February 2020 ‘Concerns have been raised about the ethics approval and informed consent procedures related to the research reported in this paper. The paper includes the following author declarations: “After informed consent, blood samples of 1129 unrelated healthy individuals were obtained. This work was approved by the Ethics Committee of the Institute of Forensic Science, Ministry of Public Security, People’s Republic of China”. Editorial action will be taken as appropriate once an investigation of the concerns is complete and all parties have been given an opportunity to respond in full.’

Abstract

Ili is located in northernmost Xinjiang, China. The Uyghur population only accounts for 15.90% of the total population in the nation. There is currently no large population data-based data set in Ili Uyghur. In this study, we investigated the genetic diversities of 18 autosomal short tandem repeat (STR) loci in 1129 Uyghur individuals living in Ili. The values of combined power of discrimination (CPD) and combined probability of exclusion (CPE) were 0.99999999999999999999990244 and 0.99999995645, respectively. Furthermore, we explored the genetic relationships between the Ili Uyghur population and 32 previously published populations. The results indicated that the Ili Uyghur population was more closely related to the Xinjiang Kazakh population. In addition, It was worth noting that significant differences were observed between Ili the Uyghur population and the Uyghur1 and Uyghur2 populations at the shared 15 loci, with significant differences at 7 and 11 loci after Bonferroni adjustment (p = 0.05/495 ≈ 0.00010).

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  • 26 February 2020

    ‘Concerns have been raised about the ethics approval and informed consent procedures related to the research reported in this paper. The paper includes the following author declarations: “After informed consent, blood samples of 1129 unrelated healthy individuals were obtained. This work was approved by the Ethics Committee of the Institute of Forensic Science, Ministry of Public Security, People’s Republic of China”. Editorial action will be taken as appropriate once an investigation of the concerns is complete and all parties have been given an opportunity to respond in full.’

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Acknowledgments

We thank all of the participants of this study.

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Correspondence to Jian Ye.

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The authors declare that they have no conflict of interest.

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Li, Z., Zhang, J., Zhang, Y. et al. Genetic diversities and phylogenetic analysis of 18 autosomal STR loci in the Uyghur population living in Ili, Northwest China. Int J Legal Med 133, 771–773 (2019). https://doi.org/10.1007/s00414-018-1872-y

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Keywords

  • Genetic polymorphisms
  • Short tandem repeat
  • Uyghur population
  • Ili