Development of the Kazakhstan Y-chromosome haplotype reference database: analysis of 27 Y-STR in Kazakh population

Abstract

To improve available databases of forensic interest, all Y-STR haplotypes from Kazakh population were presented in this study. The reference database accumulated almost 3650 samples from academic and citizen science. Additionally, 27 Y-STR from Yfiler Plus System were first analyzed in 300 males from Kazakh (Qazaq) populations residing in Kazakhstan. The data is available in the YHDR under accession numbers YA004316 and YA004322. A total of 270 unique haplotypes were observed. Discrimination capacity was 90%. Obtained Y-STR haplotypes exhibited a high intra-population diversity. Analysis of pairwise genetic distances showed lowest RST values from Uighur and Mongolian populations.

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Acknowledgments

We gratefully acknowledge all sample donors who participated in this study. We thank Nazarbayev University students (Aigul Abilmazhinova, Rassul Khakimov, Azamat Bashabayev, Kamila Issabayeva, Dariya Kassybayeva, Akylzhan Zhaken) for the laboratory assistance. We would like to thank Maxim Solomadin and Ayken Askapuli for contributions to this work.

Funding

This study received primary support from the Ministry of Education and Science of the Republic of Kazakhstan (Grant No. AP05134955).

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Authors

Contributions

Conceived and designed the experiments: MZ, AA; performed the experiments: AS, IT, DE, SL, AE; analyzed the data: MZ, AS; contributed reagents/materials/analysis tools: AR, AA, SL, AE, IT; wrote the paper: MZ; AS, AA participated in the drafting; study initiation: MZ; read and approved the final version of the paper: all coauthors.

Corresponding author

Correspondence to Maxat Zhabagin.

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Competing interests

The authors declare that they have no competing interests.

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Zhabagin, M., Sarkytbayeva, A., Tazhigulova, I. et al. Development of the Kazakhstan Y-chromosome haplotype reference database: analysis of 27 Y-STR in Kazakh population. Int J Legal Med 133, 1029–1032 (2019). https://doi.org/10.1007/s00414-018-1859-8

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Keywords

  • Central Asia
  • Kazakh
  • Y chromosome
  • YHRD
  • Forensic
  • Population genetics
  • STR