Genetic polymorphisms of 32 Y-STR loci in Meizhou Hakka population
Using AGCU Y24 Plus PCR Amplification Kit, 32 Y short tandem repeat (STR) loci were analyzed in 355 unrelated male participants of Meizhou city in Guangdong Province of China. By analyzing 341 different haplotypes, it was found that haplotype diversity (HD) and discrimination capacity (DC) were 0.9995 and 0.9605, respectively. Population relationships were analyzed by comparing Hakka population with ten other populations. The results indicate that Meizhou Hakka population was closely related to Guangdong Han population. These data were valuable for both forensic applications and population genetics.
KeywordsShort tandem repeats Y chromosome Meizhou Hakka
The authors are very grateful to all sample donors for their contributions to this work and all those who helped with sample collection. We also thank Xiaoying Yang, Chao Liu, and Yuanjian Huang, for their help with the manuscript’s revision.
This work was supported by a grant from the Natural Science Foundation of China (Grant no.81501627) and Innovative training program for College Students (Grant no. 201712121301).
Compliance with ethical standards
The study was approved by the Ethics Committee of Southern Medical University.
Conflict of interest
The authors declare that they have no conflict of interest.
- 5.Wang Y, Zhang YJ, Zhang CC, Li R, Yang Y, Ou XL, Tong DY, Sun HY (2016) Genetic polymorphisms and mutation rates of 27 Y-chromosomal STRs in a Han population from Guangdong Province, Southern China. Forensic Sci Int Genet 21:5–9. https://doi.org/10.1016/j.fsigen.2015.09.013 CrossRefPubMedGoogle Scholar