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Genetic portrait of Tamil non-tribal and Irula tribal population using Y chromosome STR markers

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Abstract

The 17 Y chromosomal short tandem repeat loci included in the AmpFlSTR® Yfiler™ PCR Amplification Kit were used to analyse the genetic diversity of 517 unrelated males representing the non-tribal and Irula tribal population of Tamil Nadu. A total of 392 unique haplotypes were identified among the 400 non-tribal samples whereas 111 were observed among the 117 Irula tribal samples. Rare alleles for the loci DYS458, DYS635 and YGATAH4.1 were also observed in both population. The haplotype diversity for the non-tribal and Irula tribal population were found to be 0.9999, and the gene diversity ranged from 0.2041 (DYS391) to 0.9612 (DYS385). Comparison of the test population with 26 national and global population using principal coordinate analysis (PCoA) and determination of the genetic distance matrix using phylogenetic molecular analysis indicate a clustering of the Tamil Nadu non-tribal and Irula tribal population away from other unrelated population and proximity towards some Indo-European (IE) and Asian population. Data are available in the Y chromosome haplotype reference database (YHRD) under accession number YA004055 for Tamil non-tribal and YA004056 for the Irula tribal group.

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Acknowledgments

The authors would like to thank all the blood donors who contributed to this study.

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The authors declare that they have no competing interests.

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Authors and Affiliations

  1. Forensic Sciences Department, Mylapore, Chennai, Tamil Nadu, 600 004, India

    Rajshree Raghunath, Kamalakshi Krishnamoorthy & Lakshmi Balasubramanian

  2. Department of Biotechnology, SRM University, Kattankulathur, Chennai, Tamil Nadu, 603 203, India

    Rajshree Raghunath & Lakshmi Balasubramanian

  3. SRM Research Institute, SRM University, Kattankulathur, Chennai, Tamil Nadu, 603 203, India

    Ramkumar Kunka Mohanram

Authors
  1. Rajshree Raghunath
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  2. Kamalakshi Krishnamoorthy
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  3. Lakshmi Balasubramanian
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  4. Ramkumar Kunka Mohanram
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Corresponding author

Correspondence to Rajshree Raghunath.

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Raghunath, R., Krishnamoorthy, K., Balasubramanian, L. et al. Genetic portrait of Tamil non-tribal and Irula tribal population using Y chromosome STR markers. Int J Legal Med 130, 367–369 (2016). https://doi.org/10.1007/s00414-015-1207-1

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  • DOI: https://doi.org/10.1007/s00414-015-1207-1

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