Skip to main content

Genetic polymorphism of 17 Y chromosomal STRs in Kazakh and Uighur populations from Xinjiang, China

Abstract

To evaluate the utility of Y-STR data for DNA testing in two ethnic populations of Xinjiang province, a sample of 338 subjects (121 Kazakhs and 217 Uighurs) was tested. In the Kazakh and Uighur populations, the haplotype diversity was 0.868 and 0.996, respectively, and the discrimination capacity was 0.5950 and 0.8940, respectively. High numbers of singleton haplotypes were observed among Xinjiang Uighurs, but fewer were found in Kazakhs. Our results were also compared with geographically and linguistically close populations.

This is a preview of subscription content, access via your institution.

References

  1. Yao YG, Kong QP, Wang CY, Zhu CL, Zhang YP (2004) Different matrilineal contributions to genetic structure of ethnic groups in the Silk Road region in China. Mol Biol Evol 21:2265–2280

    CAS  PubMed  Article  Google Scholar 

  2. Erhart D, Berger B, Niederstätter H, Gassner C, Schennach H, Parson W (2012) Frequency data for 17 Y-chromosomal STRs and 19 Y-chromosomal SNPs in the Tyrolean district of Reutte, Austria. Int J Legal Med 126:977–978

    PubMed  Article  Google Scholar 

  3. Schneider S, Roessli D, Excoffier L (2011) Arlequin ver 3.5.1.3: a software for population genetics data analysis, genetics and biometry laboratory. University of Geneva, Switzerland

    Google Scholar 

  4. Tarlykov RV, Zholdybayeva EV, Akilzhanova AR, Nurkina ZM, Rakhypbekov TK, Ramanculov EM (2013) Mitochondrial and Y-chromosomal profile of the Kazakh population from East Kazakhstan. Croat Med J 54:17–24

    PubMed Central  PubMed  Article  Google Scholar 

  5. Dulik MC, Osipova LP, Schurr TG (2011) Y-Chromosome Variation in Altaian Kazakhs Reveals a Common Paternal Gene Pool for Kazakhs and the Influence of Mongolian Expansions. PLos one 6(3):1–12

    Article  Google Scholar 

  6. Parson W, Roewer L (2010) Publication of population data of linearly inherited DNA markers in the International Journal of Legal Medicine. Int J Legal Med 124:505–509

    PubMed  Article  Google Scholar 

  7. Poetsch M, Bajanowski T, Pfeiffer H (2012) The publication of population genetic data in the International Journal of Legal Medicine: guidelines. Int J Legal Med 126:489–490

    Article  Google Scholar 

Download references

Acknowledgments

We are deeply thankful for all donors who contributed their DNA sample to this study. This work was supported by the grants from Natural Science Foundation of China (31260267), Heart and Stroke Foundation of Canada, “Tianshan Scholar” Project and Doctor Start funding (BS110120) of Xinjiang University.

Conflict of interest

The authors declare that they have no conflict of interest.

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Zhenghai Ma or Xiufen Zheng.

Electronic Supplementary Material

Below is the link to the electronic supplementary material.

Supplementary Figure S1

The multidimensional scaling plot based on 7 Y-chromosome short tandem repeat loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392 and DYS393). XJKAZ: Xinjiang Kazakh (this study); XJUIG: Xinjiang Uighur (this study); EHKAZ: East Kazakhstan Kazakh (YA003700) [1]; RKAZ: Altai Kazakh [2]; KAZ1: Kazakh 1 [3]; UIG1: Uighur 1 [3]; UIG2: Uighur 2 [4]; MNG1: Monglian 1 [5]; MNG2: Monglian 2 [4]; UZB: Uzbek [5]; CA: Central Asia [6]; TJK: Tajik [5]; KRZ: Kyrgyz [3-5]; UIG3: Urumqi Uighurs (YA003237); UIG4: Yili Uighurs (YA003241); UIG5: Yining/Xinjiang Uighurs (YA003297); SHKAZ: South Kazakhstan Kazakh (YA003729); THKAZ: Taraz, Kazakhstan Kazakhs (YA003280). (PPT 84 kb)

Supplementary Table S1

Y-chromosome short tandem repeat haplotypes of Uighur and Kazakh populations (XLS 73.5 kb)

Supplementary Table S2

Allele frequency patterns of 17 Y-chromosome short tandem repeat loci in Uighur and Kazakh populations (XLS 45 kb)

Supplementary Table S3

Pairwise genetic distances based on analysis of 7 Y-STR loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392 and DYS393) between Xinjiang Kazakh and Uighur populations and other 16 populations. P values are shown above, Fst values below the diagonal. (XLS 39 kb)

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Shan, W., Ablimit, A., Zhou, W. et al. Genetic polymorphism of 17 Y chromosomal STRs in Kazakh and Uighur populations from Xinjiang, China. Int J Legal Med 128, 743–744 (2014). https://doi.org/10.1007/s00414-013-0948-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00414-013-0948-y

Keywords

  • Y-STR
  • Kazakh
  • Uighur
  • Gene diversity
  • Polymorphism