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Genetic polymorphism of 17 Y chromosomal STRs in Kazakh and Uighur populations from Xinjiang, China


To evaluate the utility of Y-STR data for DNA testing in two ethnic populations of Xinjiang province, a sample of 338 subjects (121 Kazakhs and 217 Uighurs) was tested. In the Kazakh and Uighur populations, the haplotype diversity was 0.868 and 0.996, respectively, and the discrimination capacity was 0.5950 and 0.8940, respectively. High numbers of singleton haplotypes were observed among Xinjiang Uighurs, but fewer were found in Kazakhs. Our results were also compared with geographically and linguistically close populations.

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We are deeply thankful for all donors who contributed their DNA sample to this study. This work was supported by the grants from Natural Science Foundation of China (31260267), Heart and Stroke Foundation of Canada, “Tianshan Scholar” Project and Doctor Start funding (BS110120) of Xinjiang University.

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The authors declare that they have no conflict of interest.

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Correspondence to Zhenghai Ma or Xiufen Zheng.

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Supplementary Figure S1

The multidimensional scaling plot based on 7 Y-chromosome short tandem repeat loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392 and DYS393). XJKAZ: Xinjiang Kazakh (this study); XJUIG: Xinjiang Uighur (this study); EHKAZ: East Kazakhstan Kazakh (YA003700) [1]; RKAZ: Altai Kazakh [2]; KAZ1: Kazakh 1 [3]; UIG1: Uighur 1 [3]; UIG2: Uighur 2 [4]; MNG1: Monglian 1 [5]; MNG2: Monglian 2 [4]; UZB: Uzbek [5]; CA: Central Asia [6]; TJK: Tajik [5]; KRZ: Kyrgyz [3-5]; UIG3: Urumqi Uighurs (YA003237); UIG4: Yili Uighurs (YA003241); UIG5: Yining/Xinjiang Uighurs (YA003297); SHKAZ: South Kazakhstan Kazakh (YA003729); THKAZ: Taraz, Kazakhstan Kazakhs (YA003280). (PPT 84 kb)

Supplementary Table S1

Y-chromosome short tandem repeat haplotypes of Uighur and Kazakh populations (XLS 73.5 kb)

Supplementary Table S2

Allele frequency patterns of 17 Y-chromosome short tandem repeat loci in Uighur and Kazakh populations (XLS 45 kb)

Supplementary Table S3

Pairwise genetic distances based on analysis of 7 Y-STR loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392 and DYS393) between Xinjiang Kazakh and Uighur populations and other 16 populations. P values are shown above, Fst values below the diagonal. (XLS 39 kb)

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Shan, W., Ablimit, A., Zhou, W. et al. Genetic polymorphism of 17 Y chromosomal STRs in Kazakh and Uighur populations from Xinjiang, China. Int J Legal Med 128, 743–744 (2014).

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  • Y-STR
  • Kazakh
  • Uighur
  • Gene diversity
  • Polymorphism