Pump injector system applied to targeted post-mortem coronary artery angiography
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Targeted post-mortem computed tomography angiography (PMCTA) is one of several methods described that can be used to investigate the coronary arteries after death. Previously, this particular method has involved the manual injection of contrast media. However, manual systems do not mimic physiological conditions (arterial pressure) and may not provide optimal contrast, as iodinated contrast medium dissipates rapidly from the intra- to the extra-vascular space. To try and overcome these problems, we now report the use of a clinical automatic pump injector for targeted PMCTA. We present our final protocol for this pump system developed from experience of 74 cases, showing how these clinical pumps can be translated from clinical into autopsy practice for the injection of air and positive contrast media to visualise the coronary arteries of cadavers.
KeywordsForensic Autopsy Post-mortem Targeted Angiography Computed tomography Air Contrast Pump injector
This project is funded by a National Institute of Health (Research for Innovation, Speculation and Creativity) research grant (Grant Reference Number: RC-PG-0309-10052). The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health.
We wish to thank the relatives who consented for their recently departed loved ones to be part of this study. We wish to thank H.M. Coroner offices for North and South Leicestershire for their support of this project as well as our study co-ordinator T Visser and the porters, morticians and radiographers, who support this project.
Conflict of interest
This study has an associated patent pending related to the development of a cadaver-specific angiography catheter and the protocol related to its use.
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