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Genetic data of nine non-CODIS STRs in Chinese Han population from Guangdong Province, Southern China

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Nine non-combined DNA index system tetranucleotide short tandem repeat (STR) loci D2S1772, D6S1043, D7S3048, D8S1132, D11S2368, D12S391, D13S325, D18S1364, and GATA198B05 were amplified in a multiplex polymerase chain reaction system. The distribution of alleles of the nine STRs was reported from a Chinese Han population in Guangdong Province, Southern China. The combined power of exclusion in trios and duos for the nine loci was 0.999981 and 0.999025, respectively. Mutation rates range from 0 to 0.005618. Pairwise analysis of linkage disequilibrium, which included PowerPlex 16 System loci, did show statistically significant deviation from independence even though loci locate on the same chromosomes. The nine STRs are highly informative and suitable to extend the results obtained with other STRs commonly analyzed for difficult paternity and kinship analysis.

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  1. Lee HS, Lee JW, Han GR, Hwang JJ (2000) Motherless case in paternity testing. Forensic Sci Int 114:57–65

    Article  CAS  PubMed  Google Scholar 

  2. Fung WK, Wong DM, Chung YK (2003) How well do serial tandem repeat loci perform in excluding paternity in relatives of the biologic father among immigration cases? Transfusion 43:982–983

    Article  PubMed  Google Scholar 

  3. von Wurmb-Schwark N, Malyusz V, Simeoni E, Lignitz E, Poetsch M (2006) Possible pitfalls in motherless paternity analysis with related putative fathers. Forensic Sci Int 159:92–97

    Article  Google Scholar 

  4. Junge A, Brinkmann B, Fimmers R, Madea B (2006) Mutations or exclusion: an unusual case in paternity testing. Int J Legal Med 120:360–363

    Article  CAS  PubMed  Google Scholar 

  5. Wenk RE, Chiafari FA, Gorlin J, Polesky HF (2003) Better tools are needed for parentage and kinship studies. Transfusion 43:979–981

    Article  PubMed  Google Scholar 

  6. Gaytmenn R, Hildebrand DP, Sweet D, Pretty IA (2002) Determination of the sensitivity and specificity of sibship calculations using AmpF/STR Profiler Plus. Int J Legal Med 116:161–164

    Article  CAS  PubMed  Google Scholar 

  7. Betz T, Immel UD, Kleiber M, Klintschar M (2007) “Paterniplex”, a highly discriminative decaplex STR multiplex tailored for investigating special problems in paternity testing. Electrophoresis 28:3868–3874

    Article  CAS  PubMed  Google Scholar 

  8. Grubwieser P, Zimmermann B, Niederstatter H, Pavlic M, Steinlechner M, Parson W (2007) Evaluation of an extended set of 15 candidate STR loci for paternity and kinship analysis in an Austrian population sample. Int J Legal Med 121:85–89

    Article  CAS  PubMed  Google Scholar 

  9. Phillips CP, Syndercombe Court D, Lareu MV, Hasskamp J, Carracedo A (1998) Band shift analysis of three base-pair repeat alleles in the short tandem repeat locus D12S391. Forensic Sci Int 93:79–88

    Article  CAS  PubMed  Google Scholar 

  10. Peakall R, Smouse P (2006) genalex 6: genetic analysis in Excel. Population genetic software for teaching and research. Mol Ecol Notes 6:288–295

    Article  Google Scholar 

  11. Excoffier L, Laval G, Schneider S (2005) Arlequin (version 3.0): an integrated software package for population genetics data analysis. Evol Bioinform Online 1:47–50

    CAS  PubMed  Google Scholar 

  12. Su XL, Li DX, Liu SP, Bi LF, Wang PY, Yun TYW, Yun S (2004) Population studies on two native Mongolian population groups in China using STR loci. Forensic Sci Int 141:197–199

    Article  CAS  PubMed  Google Scholar 

  13. Schmid D, Anslinger K, Rolf B (2005) Allele frequencies of the ACTBP2 (=SE33), D18S51, D8S1132, D12S391, D2S1360, D3S1744, D5S2500, D7S1517, D10S2325 and D21S2055 loci in a German population sample. Forensic Sci Int 151:303–305

    Article  CAS  PubMed  Google Scholar 

  14. Kuzniar P, Jastrzebska E, Ploski R (2006) Validation of nine non-CODIS STR loci for forensic use in a population from Central Poland. Forensic Sci Int 159:258–260

    Article  CAS  PubMed  Google Scholar 

  15. Shi M, Yu X, Baia R, Shu X, Zhu G, Lv J, Tu Y (2008) Genetic polymorphism of 14 non-CODIS STR loci for forensic use in southeast China population. Forensic Sci Int 174:76–79

    Article  CAS  Google Scholar 

  16. Wang Z, Wang YY, Zhou B, Du B, Zhang BL, Zhang GQ, Jia Y, Zhu YH, Wei YS, Zhang L (2007) Allele frequency of D13S325 and D13S892 in two populations. J Forensic Sci 52:226–226

    Article  PubMed  Google Scholar 

  17. Weir BS (1996) Genetic data analysis II: methods for discrete population genetic data. Sinauer Associates, Sunderland

    Google Scholar 

  18. Brinkmann B, Klintschar M, Neuhuber F, Huhne J, Rolf B (1998) Mutation rate in human microsatellites: influence of the structure and length of the tandem repeat. Am J Hum Genet 62:1408–1415

    Article  CAS  PubMed  Google Scholar 

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Correspondence to De-Jian Lu.

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Lu, DJ., Liu, QL. & Zhao, H. Genetic data of nine non-CODIS STRs in Chinese Han population from Guangdong Province, Southern China. Int J Legal Med 125, 133–137 (2011).

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