International Journal of Legal Medicine

, Volume 122, Issue 3, pp 251–255 | Cite as

Analysis of Y-chromosomal SNP haplogroups and STR haplotypes in an Algerian population sample

  • C. Robino
  • F. Crobu
  • C. Di Gaetano
  • A. Bekada
  • S. Benhamamouch
  • N. Cerutti
  • A. Piazza
  • S. Inturri
  • C. Torre
Short Communication

Abstract

The distribution of Y-chromosomal single nucleotide polymorphism (SNP) haplogroups and short tandem repeat (STR) haplotypes was determined in a sample of 102 unrelated men of Arab origin from northwestern Algeria (Oran area). A total of nine different haplogroups were identified by a panel of 22 binary markers. The most common haplogroups observed in the Algerian population were E3b2 (45.1%) and J1 (22.5%). Y-STR typing by a 17-loci multiplex system allowed 93 haplotypes to be defined (88 were unique). Striking differences in the allele distribution and gene diversity of Y-STR markers between haplogroups could be found. In particular, intermediate alleles at locus DYS458 specifically characterized the haplotypes of individuals carrying haplogroup J1. All the intermediate alleles shared a common repeat sequence structure, supporting the hypothesis that the variant originated from a single mutational event.

Keywords

Y chromosome Single nucleotide polymorphism Short tandem repeat Algeria DYS458 

Supplementary material

414_2007_203_MOESM1_ESM.pdf (15 kb)
Fig. S1NJ tree forAlgerian Arabs “A-AR”(n = 102) and 11 reference populations: Algerian Berbers “A-B”(n = 16), northern “E-N”(n = 47) and southern Egyptians “E-S”(n = 50) [14]; Moroccan Arabs “M-AR”(n = 60), Moroccan Berbers “M-B”(n = 49) [18]; Andalusians“T-AN”(n = 132) and cosmopolitan (Tunisi) “T-T”Tunisians (n = 54) [19]; Tunisian Berbers “T-B”(n = 66) [20]; Portuguese “POR”(n = 250) [21]; Sicilians “SIC”(n = 255) [22]; Spaniards from Andalusia “SPA”(n = 56) [23] (PDF 14 KB)
414_2007_203_MOESM2_ESM.xls (28 kb)
Table S1Complete Y-SNP typing results and haplogroups observed in the Algerian population sample (XLS 28 KB)
414_2007_203_MOESM3_ESM.xls (32 kb)
Table S2Complete list of Y-chromosomal haplotypes observed in the Algerian population sample (XLS 32 KB)
414_2007_203_MOESM4_ESM.pdf (29 kb)
Table S3Pairwise distance (RST) between Algerian Arabs (A-AR) and eleven reference populations: Algerian Berbers “A-B” (n = 16), northern “E-N” (n = 47) and southern Egyptians “E-S” (n = 50) [14]; Moroccan Arabs “M-AR” (n = 60), Moroccan Berbers “M-B” (n = 49) [18]; Andalusians “T-AN” (n = 132) and cosmopolitan (Tunisi) “T-T” Tunisians (n = 54) [19]; Tunisian Berbers “T-B” (n = 66) [20]; Portuguese “POR” (n = 250) [21]; Sicilians “SIC” (n = 255) [22]; Spaniards from Andalusia “SPA” (n = 56) [23]. RST and p values are shown below and above the diagonal, respectively. Significant comparisons are shown in bold (PDF 30 KB)
414_2007_203_MOESM5_ESM.pdf (24 kb)
Table S4Most frequent Y-STR alleles within major haplogroups found in the Algerian population sample (unique alleles are underlined) (PDF 24 KB)

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Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • C. Robino
    • 1
  • F. Crobu
    • 2
  • C. Di Gaetano
    • 2
  • A. Bekada
    • 3
  • S. Benhamamouch
    • 3
  • N. Cerutti
    • 2
  • A. Piazza
    • 2
  • S. Inturri
    • 1
  • C. Torre
    • 1
  1. 1.Department of Anatomy, Pharmacology and Legal MedicineUniversity of TurinTurinItaly
  2. 2.Department of Genetics, Biology and BiochemistryUniversity of TurinTurinItaly
  3. 3.Département de Biotechnologie, Faculté des SciencesUniversité d’OranOranAlgeria

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