To define the Y-chromosome genetic structure in Apennine populations, 17 Y-chromosome short tandem repeats (Y-STRs) and 37 Y-single nucleotide polymorphisms (Y-SNPs) were typed in 162 subjects living in the upland area of the Marches (Central Italy). A total number of 155 haplotypes (haplotype diversity was 0.9994) and 14 SNP haplogroups were observed. Testing high-resolution Y-chromosome data sets, e.g. using Yfiler and SNPs, increases the discriminatory capacity in individual identification for forensic purposes. It is also useful in autochthonous population and micro-population studies to highlight the most informative loci for evolutionary aims.
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Special thanks go to Dr. M. Piani and to all volunteers. This study was supported by a grant from the Ministero per l’Istruzione, l’Università e la Ricerca (MIUR grant no. 2005064329_002).
Electronic supplementary material
Below is the link to the electronic supplementary material.
Y-chromosome haplotypes and corresponding Y-SNP haplogroups in 162 unrelated individuals from the Marches Apennine (Central Italy) (DOC 572 kb)
Relative allele frequencies and gene diversities (GD) of Y-STR markers in the Marches sample (the most frequent allele is in bold type). Notes refer to alleles observed as unique in the 5 most frequent regrouping haplogroups (E3b, I, J2, G, R1) (DOC 131 kb)
Genotyping frequencies and gene diversity (GD) of DYS385 multi-copy locus (DOC 45 kb)
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Onofri, V., Alessandrini, F., Turchi, C. et al. Y-chromosome genetic structure in sub-Apennine populations of Central Italy by SNP and STR analysis . Int J Legal Med 121, 234–237 (2007). https://doi.org/10.1007/s00414-007-0153-y
- Short tandem repeats
- Single nucleotide polymorphisms
- Population data