Skip to main content
SpringerLink
Log in

Sequence structure and population data of two X-linked markers: DXS7423 and DXS8377

  • Short Communication
  • Published:
International Journal of Legal Medicine Aims and scope Submit manuscript

Abstract.

DXS7423 and DXS8377 are two microsatellite markers located in the q28 band of chromosome X. We developed a protocol to amplify both markers in a single reaction, sequenced the most common alleles and studied allele frequencies in a Spanish population sample. DXS7423 allele variability was due to different numbers of (TCCA) repeats and five different alleles were found with apparent sizes between 181 and 197 bp. The probability of discrimination (PD) was 87% for female samples, and the expected probability of exclusion (PE) was 71%. DXS8377 appeared as a highly polymorphic marker with variable numbers of (CTC), (TCC) and (TTC) repeats. We found 18 alleles of different sizes (204–258 bp) and the PD and PE were 99% and 93%, respectively. These data suggest that DXS7423 and DXS8377 can be very useful markers for genetic forensic studies.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Author information

Authors and Affiliations

  1. Unit of Legal Medicine, Faculty of Medicine, University of Cantabria, Av. Herrera Oria s/n, 39011 Santander, Spain, , , , ,

    María T. Zarrabeitia & Carolina Sañudo

  2. Unit of Internal Medicine, Faculty of Medicine, University of Cantabria, Santander, Spain, , , , ,

    José A. Riancho

  3. Unit of Pediatrics, Faculty of Medicine, University of Cantabria, Santander, Spain, , , , ,

    Teresa Amigo

  4. Department of Zoology, Faculty of Pharmacy, University of Basque Country, Vitoria, Spain, , , , ,

    Marian de Pancorbo

Authors
  1. María T. Zarrabeitia
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Teresa Amigo
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Carolina Sañudo
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Marian de Pancorbo
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. José A. Riancho
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Electronic Publication

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zarrabeitia, M.T., Amigo, T., Sañudo, C. et al. Sequence structure and population data of two X-linked markers: DXS7423 and DXS8377. Int J Legal Med 116, 368–371 (2002). https://doi.org/10.1007/s00414-002-0316-9

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00414-002-0316-9

Search

Navigation