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Direct visualisation of individual gene organisation in Trypanosoma brucei by high-resolution in situ hybridisation

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Abstract. 

We achieved the direct visualisation of gene organisation in Trypanosoma brucei using fluorescent in situ hybridisation on extended nuclear DNA fibres. We demonstrated the repetitive nature of the tubulin gene cluster, which consists of up to 19 α- and β-tubulin genes arranged in tandem repeats.

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Authors and Affiliations

  1. School of Biological Sciences, 2.205 Stopford Building, University of Manchester, Manchester M13 9PT, UK, , , , , , GB

    Klaus Ersfeld, Karin Asbeck & Keith Gull

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  1. Klaus Ersfeld
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  2. Karin Asbeck
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  3. Keith Gull
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Received: 16 January 1998

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Ersfeld, K., Asbeck, K. & Gull, K. Direct visualisation of individual gene organisation in Trypanosoma brucei by high-resolution in situ hybridisation. Chromosoma 107, 237–240 (1998). https://doi.org/10.1007/s004120050302

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  • DOI: https://doi.org/10.1007/s004120050302

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