Skip to main content
Log in

Safety concerns related to magnetic field exposure

  • Review
  • Published:
Radiation and Environmental Biophysics Aims and scope Submit manuscript

Abstract

The recent development of superconducting magnets has resulted in a huge increase in human exposure to very large static magnetic fields of up to several teslas (T). Considering the rapid advances in applications and the great increases in the strength of magnetic fields used, especially in magnetic resonance imaging, safety concerns about magnetic field exposure have become a key issue. This paper points out some of these safety concerns and gives an overview of the findings about this theme, focusing mainly on mechanisms of magnetic field interaction with living organisms and the consequent effects.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Notes

  1. Paramagnetism is the tendency of the atomic magnetic dipoles to align with an external magnetic field. Paramagnetic materials are attracted when subjected to an applied magnetic field. Diamagnetism is a property of all materials and opposes applied magnetic fields, but is very weak. Paramagnetism, when present, is stronger than diamagnetism and produces magnetization in the direction of the applied field, and proportional to the applied field.

References

  1. Schenck JF (2000) Safety of strong, static magnetic fields. J Magn Reson Imaging 12:2–19

    Article  PubMed  CAS  Google Scholar 

  2. Schenck JF (2005) Physical interactions of static magnetic fields with living tissues. Prog Biophys Mol Biol 87:185–204

    Article  PubMed  Google Scholar 

  3. Chakeres DW, de Vocht F (2005) Static magnetic field effects on human subjects related to magnetic resonance imaging systems. Prog Biophys Mol Biol 87:255–265

    Article  PubMed  Google Scholar 

  4. Gowland PA (2005) Present and future magnetic resonance sources of exposure to static fields. Prog Biophys Mol Biol 87:175–183

    Article  PubMed  CAS  Google Scholar 

  5. Marzola P, Osculati F, Sbarbati A (2003) High field MRI in preclinical research. Eur J Radiol 48:165–170

    Article  PubMed  Google Scholar 

  6. Takahashi M, Uematsu H, Hatabu H (2003) MR imaging at high magnetic fields. Eur J Radiol 46:45–52

    Article  PubMed  Google Scholar 

  7. Scarabino T, Nemore F, Giannatempo GM, Bertolino A, Di Salle F, Salvolini U (2003) 3.0 T magnetic resonance in neuroradiology. Eur J Radiol 48:154–164

    Article  PubMed  Google Scholar 

  8. FDA (2003) Criteria for significant risk investigations of magnetic resonance diagnostic devices. www.fda.gov/cdrh/ode/guidance/793.pdf

  9. Liu F, Zhao HW, Crozier S (2003) Calculation of electric fields induced by body and head motion in high-field MRI. J Magn Reson 161:99–107

    Article  PubMed  CAS  Google Scholar 

  10. van Deventer TE, Saunders R, Repacholi MH (2005) WHO health risk assessment process for static fields. Prog Biophys Mol Biol 87:355–363

    Article  PubMed  Google Scholar 

  11. Ikehata M, Koana T, Suzuki Y, Shimizu H, Nakagawa M (1999) Mutagenicity and co-mutagenicity of static magnetic fields detected by bacterial mutation assay. Mutat Res—Fundam Mol Mech Mutagen 427:147–156

    Article  CAS  Google Scholar 

  12. Higashi T, Yamagishi A, Takeuchi T, Date M (1995) Effects of static magnetic-fields on erythrocyte rheology. Bioelectrochem Bioenerg 36:101–108

    Article  CAS  Google Scholar 

  13. Sienkiewicz Z (2005) Rapporteur report: implications for exposure guidelines. Prog Biophys Mol Biol 87:365–372

    Article  PubMed  Google Scholar 

  14. Grissom CB (1995) Magnetic-field effects in biology—a survey of possible mechanisms with emphasis on radical-pair recombination. Chem Rev 95:3–24

    Article  CAS  Google Scholar 

  15. Tenforde TS (2005) Magnetically induced electric fields and currents in the circulatory system. Prog Biophys Mol Biol 87:279–288

    Article  PubMed  Google Scholar 

  16. Gaffey CT, Tenforde TS (1983) Bioelectric properties of frog sciatic-nerves during exposure to stationary magnetic-fields. Radiat Environ Biophys 22:61–73

    Article  PubMed  CAS  Google Scholar 

  17. Holden AV (2005) The sensitivity of the heart to static magnetic fields. Prog Biophys Mol Biol 87:289–320

    Article  PubMed  Google Scholar 

  18. Hore PJ (2005) Rapporteur’s report: sources and interaction mechanisms. Prog Biophys Mol Biol 87:205–212

    Article  PubMed  CAS  Google Scholar 

  19. Chiriac AP, Simionescu CI (2000) Magnetic field polymerisation. Prog Polym Sci 25:219–258

    Article  CAS  Google Scholar 

  20. Stegemann S, Altman KI, Muhlensiepen H, Feinendegen LE (1993) Influence of a stationary magnetic-field on acetylcholinesterase in murine bone-marrow cells. Radiat Environ Biophys 32:65–72

    Article  PubMed  CAS  Google Scholar 

  21. Vajda T (1980) Investigation of magnetic-field effect on trypsin activity. Radiat Environ Biophys 18:275–280

    Article  PubMed  CAS  Google Scholar 

  22. Saffer JD, Phillips JL (1996) Evaluating the biological aspects of in vitro studies in bioelectromagnetics. Bioelectrochem Bioenerg 40:1–7

    Article  CAS  Google Scholar 

  23. Dini L, Abbro L (2005) Bioeffects of moderate-intensity static magnetic fields on cell cultures. Micron 36:195–217

    Article  PubMed  Google Scholar 

  24. Denegre JM, James M, Valles J, Lin K, Jordan WB, Mowry KL (1998) Cleavage planes in frog eggs are altered by strong magnetic fields. Proc Natl Acad Sci USA 95:14729–14732

    Article  PubMed  CAS  Google Scholar 

  25. Iwasaka M, Takeuchi M, Ueno S, Tsuda H (1998) Polymerization and dissolution of fibrin under homogeneous magnetic fields. J Appl Phys 83:6453–6455

    Article  CAS  Google Scholar 

  26. Sakurai H, Okuno K, Kubo A, Nakamura K, Shoda M (1999) Effect of a 7-tesla homogeneous magnetic field on mammalian cells. Bioelectrochem Bioenerg 49:57–63

    Article  PubMed  CAS  Google Scholar 

  27. Schiffer IB, Schreiber WG, Graf R, Schreiber EM, Jung D, Rose DM, Hehn M, Gebhard S, Sagemuller J, Spiess HW, Oesch F, Thelen M, Hengstler JG (2003) No influence of magnetic fields on cell cycle progression using conditions relevant for patients during MRI. Bioelectromagnetics 24:241–250

    Article  PubMed  Google Scholar 

  28. Wiskirchen J, Groenewaeller EF, Kehlbach R, Heinzelmann F, Wittau M, Rodemann HP, Claussen CD, Duda SH (1999) Long-term effects of repetitive exposure to a static magnetic field (1.5 T) on proliferation of human fetal lung fibroblasts. Magn Reson Med 41:464–468

    Article  PubMed  CAS  Google Scholar 

  29. Miyakoshi J (2005) Effects of static magnetic fields at the cellular level. Prog Biophys Mol Biol 87:213–223

    Article  PubMed  CAS  Google Scholar 

  30. Carnes KI, Magin RL (1996) Effects of in utero exposure to 4.7 T MR imaging conditions on fetal growth and testicular development in the mouse. Magn Reson Imaging 14:263–274

    Article  PubMed  CAS  Google Scholar 

  31. Kok RD, de Vries MM, Heerschap A, van den Berg PP (2004) Absence of harmful effects of magnetic resonance exposure at 1.5 T in utero during the third trimester of pregnancy: a follow-up study. Magn Reson Imaging 22:851–854

    Article  PubMed  Google Scholar 

  32. Gray JR, Frith CH, Parker JD (2000) In vivo enhancement of chemotherapy with static electric or magnetic fields. Bioelectromagnetics 21:575–583

    Article  PubMed  CAS  Google Scholar 

  33. Leszczynski D (2005) Rapporteur report: cellular, animal and epidemiological studies of the effects of static magnetic fields relevant to human health. Prog Biophys Mol Biol 87:247–253

    Article  PubMed  Google Scholar 

  34. Chakeres DW, Kangarlu A, Boudoulas H, Young DC (2003) Effect of static magnetic field exposure of up to 8 Tesla on sequential human vital sign measurements. J Magn Reson Imaging 18:346–352

    Article  PubMed  Google Scholar 

  35. Kangarlu A, Burgess RE, Zhu H, Nakayama T, Hamlin RL, Abduljalil AM, Robitaille PML (1999) Cognitive, cardiac, and physiological safety studies in ultra high field magnetic resonance imaging. Magn Reson Imaging 17:1407–1416

    Article  PubMed  CAS  Google Scholar 

  36. Houpt TA, Pittman DW, Riccardi C, Cassell JA, Lockwood DR, Barranco JM, Kwon B, Smith JC (2005) Behavioral effects on rats of high strength magnetic fields generated by a resistive electromagnet. Physiol Behav 86:379–389

    Article  PubMed  CAS  Google Scholar 

  37. Stokowsk LA (2005) Ensuring safety for infants undergoing magnetic resonance imaging. Adv Neonatal Care 5:14–27

    Article  Google Scholar 

  38. Formica D, Silvestri S (2004) Biological effects of exposure to magnetic resonance imaging: an overview. Biomed Eng Online 3:11

    Article  PubMed  Google Scholar 

  39. Nyenhuis JA, Park SM, Kamondetdacha R, Amjad A, Shellock FG, Rezai AR (2005) MRI and implanted medical devices: basic interactions with an emphasis on heating. IEEE Trans Device Mater Reliab 5:467–480

    Article  Google Scholar 

  40. Dempsey MF, Condon B, Hadley DM (2002) MRI safety review. Semin Ultrasound CT MR 23:392–401

    Article  PubMed  Google Scholar 

  41. Martin ET, Coman JA, Shellock FG, Pulling CC, Fair R, Jenkins K (2004) Magnetic resonance imaging and cardiac pacemaker safety at 1.5-Tesla. J Am Coll Cardiol 43:1315–1324

    Article  PubMed  Google Scholar 

  42. Gimbel JR, Kanal E (2004) Can patients with implantable pacemakers safely undergo magnetic resonance imaging? J Am Coll Cardiol 43:1325–1327

    Article  PubMed  Google Scholar 

  43. Feychting M (2005) Health effects of static magnetic fields—a review of the epidemiological evidence. Prog Biophys Mol Biol 87:241–246

    Article  PubMed  Google Scholar 

  44. De Wilde JP, Rivers AW, Price DL (2005) A review of the current use of magnetic resonance imaging in pregnancy and safety implications for the fetus. Prog Biophys Mol Biol 87:335–353

    Article  PubMed  Google Scholar 

  45. Wollman DE, Beeri MS, Weinberger M, Cheng H, Silverman JM, Prohovnik I (2004) Tolerance of MRI procedures by the oldest old. Magn Reson Imaging 22:1299–1304

    Article  PubMed  Google Scholar 

  46. van Rongen E (2005) International workshop “effects of static magnetic fields relevant to human health”—Rapporteurs report: dosimetry and volunteer studies. Prog Biophys Mol Biol 87:329–333

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to E. Sócrates T. Egito.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Silva, A.K.A., Silva, É.L., Egito, E.S.T. et al. Safety concerns related to magnetic field exposure. Radiat Environ Biophys 45, 245–252 (2006). https://doi.org/10.1007/s00411-006-0065-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00411-006-0065-0

Keywords

Navigation