Abstract
Purpose To determine the short-term and long-term adherence rates with continuous positive airway pressure (CPAP) therapy in sleep apnea patients with benign prostatic hyperplasia (BPH) compared to matched controls. Methods A case–control retrospective analysis was performed in a veterans affairs hospital. All symptomatic patients with BPH (n = 107) ever started on CPAP therapy between 2006 and 2012 were compared with controls matched for severity of sleep apnea (AHI). Adherence measures were obtained at the third and twelfth month visits. The cases included symptomatic BPH patients on active medical therapy. Diuretic use among cases and controls, and severity of nocturia among the cases were also analyzed. Results The mean AHI among cases and controls was 35.6 ± 27.3 and 35.5 ± 31 (p = 0.96). The population was male and predominantly Caucasian. There was no statistically significant difference in percent days CPAP device use ≥4 h. between symptomatic BPH patients and controls at 3-month (51.6 ± 38 vs. 47.2 ± 36; p = 0.43) and 1-year (64 ± 40.5 vs. 64.7 ± 31.3; p = 0.90) visits. The use of diuretics in the cases and controls, and the severity of nocturia in the cases did not influence adherence with CPAP therapy. Conclusions BPH or diuretic use did not affect adherence with CPAP therapy in obstructive sleep apnea. Severity of nocturia did not have any influence on adherence among the cases. BPH, regardless of the severity of nocturia, and diuretic use does not influence CPAP adherence in patients with OSA.
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References
Gay P, Weaver T, Loube D, Iber C (2006) Evaluation of positive airway pressure treatment for sleep related breathing disorders in adults. Sleep 29(3):381–401
Sin DD, Mayers I, Man GC, Pawluk L (2002) Long-term compliance rates to continuous positive airway pressure in obstructive sleep apnea: a population-based study. Chest 121(2):430–435
Wei JT, Calhoun E, Jacobsen SJ (2005) Urologic diseases in America project: benign prostatic hyperplasia. J Urol 173(4):1256–1261. doi:10.1097/01.ju.0000155709.37840.fe
Chou PS, Chang WC, Chou WP, Liu ME, Lai CL, Liu CK, Ku YC, Tsai SJ, Chou YH, Chang WP (2014) Increased risk of benign prostate hyperplasia in sleep apnea patients: a nationwide population-based study. PLoS ONE 9(3):e93081. doi:10.1371/journal.pone.0093081
Doo SW, Lee HJ, Ahn J, Kim JH, Yun JH, Yang WJ, Song YS (2012) Strong impact of nocturia on sleep quality in patients with lower urinary tract symptoms. The world journal of men’s health 30(2):123–130. doi:10.5534/wjmh.2012.30.2.123
Chartier-Kastler E, Leger D, Montauban V, Comet D, Haab F (2009) Impact of nocturia on sleep efficiency in patients with benign prostatic hypertrophy. Prog Urol 19(5):333–340. doi:10.1016/j.purol.2008.10.013
Oztura I, Kaynak D, Kaynak HC (2006) Nocturia in sleep-disordered breathing. Sleep Med 7(4):362–367. doi:10.1016/j.sleep.2005.10.004
Fitzgerald MP, Mulligan M, Parthasarathy S (2006) Nocturic frequency is related to severity of obstructive sleep apnea, improves with continuous positive airways treatment. Am J Obstet Gynecol 194(5):1399–1403. doi:10.1016/j.ajog.2006.01.048
Margel D, Shochat T, Getzler O, Livne PM, Pillar G (2006) Continuous positive airway pressure reduces nocturia in patients with obstructive sleep apnea. Urology 67(5):974–977. doi:10.1016/j.urology.2005.11.054
Russo-Magno P, O’Brien A, Panciera T, Rounds S (2001) Compliance with CPAP therapy in older men with obstructive sleep apnea. J Am Geriatr Soc 49(9):1205–1211
Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The report of an American Academy of sleep medicine task force. (1999) Sleep 22(5):667–689
El-Solh AA, Ayyar L, Akinnusi M, Relia S, Akinnusi O (2010) Positive airway pressure adherence in veterans with posttraumatic stress disorder. Sleep 33(11):1495–1500
Likar LL, Panciera TM, Erickson AD, Rounds S (1997) Group education sessions and compliance with nasal CPAP therapy. Chest 111(5):1273–1277
Willemin MC, Fry S, Peres S, Wallaert B, Mallart A (2013) Effects of an educational program in non-adherent apneic patients treated with continuous positive airway pressure. Rev Pneumol Clin 69(2):70–75. doi:10.1016/j.pneumo.2012.12.009
Meyhoff HH, Nordling J (1986) Long term results of transurethral and transvesical prostatectomy: a randomized study. Scand J Urol Nephrol 20(1):27–33
Wallace DM, Wohlgemuth WK (2014) Does race-ethnicity moderate the relationship between CPAP adherence and functional outcomes of sleep in US veterans with obstructive sleep apnea syndrome? J Clin Sleep Med 10(10):1083–1091. doi:10.5664/jcsm.4106
Wallace DM, Shafazand S, Aloia MS, Wohlgemuth WK (2013) The association of age, insomnia, and self-efficacy with continuous positive airway pressure adherence in black, white, and Hispanic U.S. veterans. J Clin Sleep Med 9(9):885–895. doi:10.5664/jcsm.2988
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Metta, R.V.V.S., Zaka, A., Lee, V.C. et al. Continuous Positive Airway Pressure Adherence In Patients with Obstructive Sleep Apnea & Symptomatic BPH. Lung 195, 255–261 (2017). https://doi.org/10.1007/s00408-017-9981-9
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DOI: https://doi.org/10.1007/s00408-017-9981-9