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Pulmonary Langerhans Cell Histiocytosis and Diabetes Insipidus in Pregnant Women: Our Experience

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Abstract

Pulmonary Langerhans cell histiocytosis (PLCH) occurs predominantly in young adult smokers. Diabetes insipidus occurs in up to 15 % patients with PLCH. Information on PLCH in pregnancy is sparse, especially associated with diabetes insipidus. We report three patients with these conditions and describe the disease history and pregnancy outcomes.

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References

  1. Tazi A, Soler P, Hance AJ (2000) Adult pulmonary Langerhans’ cell histiocytosis. Thorax 55:405–416

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  2. Vassallo R, Ryu JH, Colby TV, Hartman T, Limper AH (2000) Pulmonary Langerhans’-cell histiocytosis. N Engl J Med 342:1969–1978

    Article  CAS  PubMed  Google Scholar 

  3. Sundar KM, Gosselin MV, Chung HL, Cahill BC (2003) Pulmonary Langerhans cell histiocytosis: emerging concepts in pathobiology, radiology, and clinical evolution of disease. Chest 123:1673–1683

    Article  PubMed  Google Scholar 

  4. Hance AJ, Basset F, Saumon G, Danel C, Valeyre D, Battesti JP et al (1986) Smoking and interstitial lung disease. The effect of cigarette smoking on the incidence of pulmonary histiocytosis X and sarcoidosis. Ann N Y Acad Sci 465:643–656

    Article  CAS  PubMed  Google Scholar 

  5. Maghnie M, Cosi G, Genovese E, Manca-Bitti ML, Cohen A, Zecca S et al (2000) Central diabetes insipidus in children and young adults. N Engl J Med 343:998–1007

    Article  CAS  PubMed  Google Scholar 

  6. Islinger RB, Kuklo TR, Owens BD, Horan PJ, Choma TJ, Murphey MD et al (2000) Langerhans cell histiocytosis in patients older than 21 years. Clin Orthop Relat Res 379:231–235

    Article  PubMed  Google Scholar 

  7. Howarth DM, Gilchrist GS, Mullan BP, Wiseman GA, Edmonson JH, Schomberg PJ (1999) Langerhans cell histiocytosis: diagnosis, natural history, management, and outcome. Cancer 85:2278–2290

    Article  CAS  PubMed  Google Scholar 

  8. Friedman PJ, Liebow AA, Sokoloff J (1981) Eosinophilic granuloma of lung. Clinical aspects of primary histiocytosis in the adult. Medicine 60:385–396

    Article  CAS  PubMed  Google Scholar 

  9. King TE (1992) Restrictive lung disease in pregnancy. Clin Chest Med 13:607–622

    PubMed  Google Scholar 

  10. Dimaggio LA, Lippes HA, Lee RV (1995) Histiocytosis X and pregnancy. Obstet Gynecol 85:806–809

    Article  CAS  PubMed  Google Scholar 

  11. Ogburn PL Jr, Cefalo RC, Nagel T, Okagaki T (1981) Histiocytosis X and pregnancy. Obstet Gynecol 58:513–515

    PubMed  Google Scholar 

  12. Makras P, Papadogias D, Kontogeorgos G, Piaditis G, Kaltsas GA (2005) Spontaneous gonadotrophin deficiency recovery in an adult patient with Langerhans cell histiocytosis (LCH). Pituitary 8:169–174

    Article  PubMed  Google Scholar 

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Correspondence to David Shitrit.

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Fuks, L., Kramer, M.R., Shitrit, D. et al. Pulmonary Langerhans Cell Histiocytosis and Diabetes Insipidus in Pregnant Women: Our Experience. Lung 192, 285–287 (2014). https://doi.org/10.1007/s00408-014-9559-8

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  • DOI: https://doi.org/10.1007/s00408-014-9559-8

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