Abstract
A 15-year-old male had a history of increasing dyspnea on exertion, cough, sputum production, fever, weakness, hemoptysis, and diarrhea. Chest radiography demonstrated bilateral alveolar consolidation. Bronchoalveolar lavage fluid analysis revealed extensive hemosiderin-laden alveolar macrophages. On the basis of iron deficiency anemia, diarrhea, raised antigliadin and antiendomysial antibodies, widespread villous atrophy, and crypt hyperplasia on intestinal biopsy, celiac disease was diagnosed. After treatment with a gluten-free diet, all his clinical symptoms and radiographic findings improved within two weeks.
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References
Bouros D, Panagou P, Rokkas T, Siafakas NM (1994) Bronchoalveolar lavage findings in a young adult with idiopathic pulmonary haemosiderosis and celiac disease. Eur Respir J 7:1009–1012
Edwards C, Williams A, Asoquith P (1985) Bronchopulmonary disease in celiac patients. J Clin Pathol 38:361–367
Gold WM (2000) Pulmonary function testing. In: Murray JF, Nadel JA (eds) Textbook of Respiratory Medicine, vol 1. Saunders, Philadelphia, pp 781–881
Hartl D, Belohradsky BH, Griese M, et al. (2004) Celiac disease and pulmonary hemosiderosis in a patient with chronic granulomatous disease. Pediatr Pulmonol 38:344–348
Kelly J, O’Farrely C, Rees JPR, Feighery C, Weir DGW (1987) Humoral response to alpha-gliadin as serological screening test for celiac disease. Arch Dis Child 62:469–473
Ludmerer KM, Kissane JM (1986) Hemoptysis, pulmonary infiltrates, and diarrhea in a 36-year-old man: clinicopathologic conference. Am J Med 80:930–938
Mahadeva R, Flower C, Shneerson J (1998) Bronchiectasis in association with celiac disease. Thorax 53:527–529
Malhotra P, Aggarwal R, Aggarwal AN, et al. (2005) Celiac disease as a cause of unusually severe anemia in a young man with idiopathic pulmonary haemosiderosis. Respir Med 99(4):451–453
Pacheco A, Casanova C, Fogue L, Sueiro A (1991) Long-term clinical follow-up of adult idiopathic pulmonary haemosiderosis and celiac disease. Chest 99(6):1525–1526
Perelman S, Dupuy C, Bourrillon A (1992) The Association of pulmonary hemosiderosis and celiac disease. Apropos of a new case in a child. Ann Pediatr (Paris) 39(3):185–188 (abstr)
Ploier R, Emhofer J, Dorninger L, et al. (1998) Immunological aspects of a child with idiopathic pulmonary hemosiderosis and celiac disease. Klin Padiatr 210(6):409–412
Reading R, Watson JG, Platt JW, Bird AG (1987) Pulmonary haemosiderosis and gluten. Arch Dis Child 62:513–515
Schwarz MI (1998) Diffiise alveolar hemorrhage. In: Schwarz MI, King TI (eds) Interstitial Lung Disease. B.C. Decker Inc., Hamilton- London, pp 535–558
Schwarz MI, Cherniack RM, King TE (2000) Diffuse alveolar hemorrhage and other rare infiltrative disorders. In: Murray JF, Nadel JA (eds) Textbook of Respiratory Medicine, vol 2. Saunders, Philadelphia, pp 1733–l755
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Hoca, N.T., Dayioglu, D. & Ogretensoy, M. Pulmonary Hemosiderosis in Association with Celiac Disease. Lung 184, 297–300 (2006). https://doi.org/10.1007/s00408-005-2596-6
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DOI: https://doi.org/10.1007/s00408-005-2596-6