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Cavum veli interpositi and psychotic disorder in a monocygotic twin

  • T. Supprian
  • D. Bengel
  • E. Hofmann
  • A. J. Fallgatter
  • E. Franzek
Original paper

Abstract

The case of monocygotic twins discordant for a psychotic disorder is presented. An anomaly of the septum pellucidum, a so-called cavum veli interpositi was found in the psychotic twin while his brother showed no such anomaly. Previous studies have shown a higher prevalence of septum pellucidum anomalies in schizophrenic patients. Abnormalities of the septum pellucidum may be associated with disturbed neuronal development in distinct limbic brain areas which cannot yet be visualized yet by brain imaging techniques. The finding of the cavum veli interpositi in the psychotic twin could be incidental; however, it may indicate a dysgenic process in early brain development and, thus, play a significant role in the etiology of psychosis.

Key words Septum pellucidum Developmental ¶disorder Schizophrenia Magnetic resonance imaging Cavum veli interpositi Cavum septi pellucidi 

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Copyright information

© Steinkopff Verlag 2000

Authors and Affiliations

  • T. Supprian
    • 1
  • D. Bengel
    • 2
  • E. Hofmann
    • 3
  • A. J. Fallgatter
    • 2
  • E. Franzek
    • 2
  1. 1.Department of Psychiatry, The Saarland University Hospital, D-66421 Homburg (Saar), Germany, e-mail: netsup@med-rz.uni-sb.de, Tel.: ++49 6841 164100, Fax: ++49 6841 164147DE
  2. 2.Department of Psychiatry, University of Würzburg, Füchsleinstr. 15, D-97080 Würzburg, GermanyDE
  3. 3.Department of Neuroradiology, University of Würzburg, Josef Schneider Str. 11, D-97080 Würzburg, GermanyDE

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