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Binding varicella zoster virus: an underestimated facet of insulin-degrading enzyme´s implication for Alzheimer´s disease pathology?

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Abstract

We shortly discuss a possible contribution of insulin-degrading enzyme to Alzheimer´s disease pathology by binding varicella zoster virus glycoprotein E, which increases the infectivity and cell–cell spread of the virus.

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Authors and Affiliations

  1. Department of Psychiatry and Psychotherapy, Medical Faculty, University of Magdeburg, 39120, Magdeburg, Germany

    Hans-Gert Bernstein, Henrik Dobrowolny & Johann Steiner

  2. Medical Faculty, Institute of Biochemistry and Cell Biology, University of Magdeburg, 39120, Magdeburg, Germany

    Gerburg Keilhoff

  3. Department of Psychiatry, Otto-von-Guericke University Magdeburg, Leipziger Str. 44, 39120, Magdeburg, Germany

    Hans-Gert Bernstein

Authors
  1. Hans-Gert Bernstein
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  2. Gerburg Keilhoff
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  3. Henrik Dobrowolny
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  4. Johann Steiner
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Correspondence to Hans-Gert Bernstein.

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Bernstein, HG., Keilhoff, G., Dobrowolny, H. et al. Binding varicella zoster virus: an underestimated facet of insulin-degrading enzyme´s implication for Alzheimer´s disease pathology?. Eur Arch Psychiatry Clin Neurosci 270, 495–496 (2020). https://doi.org/10.1007/s00406-019-00995-1

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  • DOI: https://doi.org/10.1007/s00406-019-00995-1

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