Abstract
Few epidemiological studies presented 12-month and lifetime prevalence estimates for DSM-IV mental disorders in the adult general population by sex and age up to very old age. From 2007 to 2010, DSM-IV mental disorders were assessed with the DIA-X/M-CIDI among N = 2400 participants (aged 29–89 years) from the Study of Health in Pomerania, an epidemiological study based on a two-stage stratified cluster sample randomly drawn from the adult general population in northeastern Germany. 36.3% of the sample was affected by any 12-month and 54.8% by any lifetime mental disorder. The most frequent diagnostic groups were anxiety (12-month: 14.8%, lifetime: 23.4%), substance use (12-month: 14.5%, lifetime: 25.0%), somatoform (12-month: 12.9%, lifetime: 20.4%) and depressive (12-month: 7.3%, lifetime: 18.6%) disorders. Except for substance use (higher prevalence in men) and bipolar disorders (comparable prevalence in men and women), higher 12-month and lifetime prevalence estimates were found in women vs. men. Moreover, lower 12-month and lifetime prevalence estimates were found in older (aged 60–74 or 75–89 years) vs. younger (aged 29–44 or 45–59 years) age groups. 22.6% (men: 21.1%, women: 23.9%) of those affected by any 12-month disorder met criteria for two and 13.6% (men: 9.6%, women: 16.9%) for three or more 12-month diagnoses. Similarly, 26.4% (men: 25.7%, women: 26.9%) of those affected by any lifetime disorder met criteria for two and 22.7% (men: 19.6%, women: 25.2%) for three or more lifetime diagnoses. Our findings demonstrate the frequency of mental disorders in northeastern Germany and emphasize the need for continued prevention and intervention efforts.
References
Alonso J, Angermeyer MC, Bernert S, Bruffaerts R, Brugha TS, Bryson H, Girolamo GD, Graaf RD, Demyttenaere K, Gasquet I (2004) Prevalence of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatr Scand 109:21–27
American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders, 4th edn. American Psychiatric Association, Washington, DC
Andreas S, Schulz H, Volkert J, Dehoust M, Sehner S, Suling A, Ausín B, Canuto A, Crawford M, Da Ronch C (2017) Prevalence of mental disorders in elderly people: The European MentDis_ICF65 + study. Br J Psychiatry 210:125–131
Andrews G, Anstey K, Brodaty H, Issakidis C, Luscombe G (1999) Recall of depressive episode 25 years previously. Psychol Med 29:787–791
Asselmann E, Beesdo-Baum K (2015) Predictors of the course of anxiety disorders in adolescents and young adults. Curr Psychiatry Rep 17:1–8
Beesdo-Baum K, Knappe S, Asselmann E, Zimmermann P, Brückl T, Höfler M, Behrendt S, Lieb R, Wittchen H-U (2015) The ‘Early Developmental Stages of Psychopathology (EDSP) study’: A 20-year review of methods and findings. Soc Psychiatry Psychiatr Epidemiol 50:851–866
Copeland WE, Wolke D, Shanahan L, Costello EJ (2015) Adult functional outcomes of common childhood psychiatric problems: a prospective, longitudinal study. JAMA Psychiatry 72:892–899
de Graaf R, Ten Have M, van Gool C, van Dorsselaer S (2012) Prevalence of mental disorders and trends from 1996 to 2009. Results from the Netherlands Mental Health Survey and Incidence Study-2. Soc Psychiatry Psychiatr Epidemiol 47:203–213
Ernst C, Angst J (1995) Depression in old age. Eur Arch Psychiatry Clin Neurosci 245:272–287
Grabe H, Meyer C, Hapke U, Rumpf H-J, Freyberger H, Dilling H, John U (2000) Prevalence, quality of life and psychosocial function in obsessive-compulsive disorder and subclinical obsessive-compulsive disorder in northern Germany. Eur Arch Psychiatry Clin Neurosci 250:262–268
Grabe HJ, Lange M, Wolff B, Völzke H, Lucht M, Freyberger H, John U, Cascorbi I (2005) Mental and physical distress is modulated by a polymorphism in the 5-HT transporter gene interacting with social stressors and chronic disease burden. Mol Psychiatry 10:220–224
Gustavsson A, Svensson M, Jacobi F, Allgulander C, Alonso J, Beghi E, Dodel R, Ekman M, Faravelli C, Fratiglioni L (2011) Cost of disorders of the brain in Europe 2010. Eur Neuropsychopharmacol 21:718–779
Heun R, Hardt J, Müller H, Maier W (1997) Selection bias during recruitment of elderly subjects from the general population for psychiatric interviews. Eur Arch Psychiatry Clin Neurosci 247:87–92
Jacobi F, Höfler M, Siegert J, Mack S, Gerschler A, Scholl L, Busch MA, Hapke U, Maske U, Seiffert I (2014) Twelve-month prevalence, comorbidity and correlates of mental disorders in Germany: the Mental Health Module of the German Health Interview and Examination Survey for Adults (DEGS1-MH). Int J Methods in Psychiatr Res 23:304–319
Jacobi F, Höfler M, Strehle J, Mack S, Gerschler A, Scholl L, Busch MA, Hapke U, Maske U, Seiffert I (2015) Twelve-months prevalence of mental disorders in the German Health Interview and Examination Survey for Adults-Mental Health Module (DEGS1-MH): a methodological addendum and correction. Int J Methods in Psychiatr Res 24:305–313
Jacobi F, Hoyer J, Wittchen H-U (2004) Seelische Gesundheit in Ost und West: Analysen auf der Grundlage des Bundesgesundheitssurveys. Zeitschrift für klinische Psychol Psychother 33:251–260
Jacobi F, Wittchen H-U, Hölting C, Höfler M, Pfister H, Müller N, Lieb R (2004) Prevalence, co-morbidity and correlates of mental disorders in the general population: results from the German Health Interview and Examination Survey (GHS). Psychol Med 34:597–611
Jorm AF (2000) Does old age reduce the risk of anxiety and depression? A review of epidemiological studies across the adult life span. Psychol Med 30:11–22
Kessler RC, Aguilar-Gaxiola S, Alonso J, Chatterji S, Lee S, Ormel J, Üstün TB, Wang PS (2009) The global burden of mental disorders: an update from the WHO World Mental Health (WMH) Surveys. Epidemiol Psychiatr Sci 18:23–33
Kessler RC, Angermeyer M, Anthony JC, De Graaf R, Demyttenaere K, Gasquet I, De Girolamo G, Gluzman S, Gureje O, Haro JM (2007) Lifetime prevalence and age-of-onset distributions of mental disorders in the World Health Organization’s World Mental Health Survey Initiative. World Psychiatry 6:168–176
Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE (2005) Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 62:593–602
Kessler RC, Birnbaum H, Bromet E, Hwang I, Sampson N, Shahly V (2010) Age differences in major depression: results from the National Comorbidity Survey Replication (NCS-R). Psychol Med 40:225–237
Kessler RC, Birnbaum HG, Shahly V, Bromet E, Hwang I, McLaughlin KA, Sampson N, Andrade LH, De Girolamo G, Demyttenaere K (2010) Age differences in the prevalence and co-morbidity of DSM-IV major depressive episodes: results from the WHO World Mental Health Survey Initiative. Depress Anxiety 27:351–364
Kessler RC, Chiu WT, Demler O, Walters EE (2005) Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 62:617–627
Kessler RC, Petukhova M, Sampson NA, Zaslavsky AM, Wittchen HU (2012) Twelve-month and lifetime prevalence and lifetime morbid risk of anxiety and mood disorders in the United States. Int J Methods in Psychiatr Res 21:169–184
Knäuper B, Wittchen H-U (1994) Diagnosing major depression in the elderly: Evidence for response bias in standardized diagnostic interviews? J Psychiatr Res 28:147–164
Mack S, Jacobi F, Beesdo-Baum K, Gerschler A, Strehle J, Höfler M, Busch MA, Maske U, Hapke U, Gaebel W (2015) Functional disability and quality of life decrements in mental disorders: Results from the Mental Health Module of the German Health Interview and Examination Survey for Adults (DEGS1-MH). Eur Psychiatry 30:793–800
Meyer C, Rumpf H-J, Hapke U, Dilling H, John U (2000) Lebenszeitprävalenz psychischer Störungen in der erwachsenen Allgemeinbevölkerung: Ergebnisse der TACOS-Studie. Der Nervenarzt 71:535–542
Moffitt TE, Caspi A, Taylor A, Kokaua J, Milne B, Polanczyk G, Poulton R (2010) How common are common mental disorders? Evidence that lifetime prevalence rates are doubled by prospective versus retrospective ascertainment. Psychol Med 40:899–909
Reed V, Gander F, Pfister H, Steiger A, Sonntag H, Trenkwalder C, Sonntag A, Hundt W, Wittchen H-U (1998) To what degree does the Composite International Diagnostic Interview (CIDI) correctly identify DSM-IV disorders? Testing validity issues in a clinical sample. Int J of Methods Psychiatr Res 7:142–155
Schmidt CO, Watzke A-B, Schulz A, Baumeister SE, Freyberger HJ, Grabe H-J (2013) Die Lebenszeitprävalenz psychischer Störungen in Vorpommern. Psychiatr Prax 40:192–199
Scott K, Von Korff M, Alonso J, Angermeyer M, Bromet E, Bruffaerts R, De Girolamo G, De Graaf R, Fernandez A, Gureje O (2008) Age patterns in the prevalence of DSM-IV depressive/anxiety disorders with and without physical co-morbidity. Psychol Med 38:1659–1669
Slade T, Johnston A, Oakley Browne MA, Andrews G, Whiteford H (2009) 2007 National survey of mental health and wellbeing: methods and key findings. Aust N Z J Psychiatry 43:594–605
StataCorp LP (2015) Stata statistical software: release 14. StataCorp, College Station
Völzke H, Alte D, Schmidt CO, Radke D, Lorbeer R, Friedrich N, Aumann N, Lau K, Piontek M, Born G (2011) Cohort profile: the study of health in pomerania. Int J Epidemiol 40:294–307
Völzke H, Alte D, Schmidt CO, Radke D, Lorbeer R, Friedrich N, Aumann N, Lau K, Piontek M, Born G, Havemann C, Ittermann T, Schipf S, Haring R, Baumeister SE, Wallaschofski H, Nauck M, Frick S, Arnold A, Junger M, Mayerle J, Kraft M, Lerch MM, Dorr M, Reffelmann T, Empen K, Felix SB, Obst A, Koch B, Glaser S, Ewert R, Fietze I, Penzel T, Doren M, Rathmann W, Haerting J, Hannemann M, Ropcke J, Schminke U, Jurgens C, Tost F, Rettig R, Kors JA, Ungerer S, Hegenscheid K, Kuhn JP, Kuhn J, Hosten N, Puls R, Henke J, Gloger O, Teumer A, Homuth G, Volker U, Schwahn C, Holtfreter B, Polzer I, Kohlmann T, Grabe HJ, Rosskopf D, Kroemer HK, Kocher T, Biffar R, John U, Hoffmann W (2011) Cohort profile: the Study of Health in Pomerania. Int J Epidemiol 40:294–307
Whiteford HA, Degenhardt L, Rehm J, Baxter AJ, Ferrari AJ, Erskine HE, Charlson FJ, Norman RE, Flaxman AD, Johns N (2013) Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010. Lancet 382:1575–1586
Wittchen H-U (1997) Strukturiertes klinisches Interview für DSM-IV: Psychische Störungen; Interviewheft und Beurteilungsheft; SKID-I. Achse I. Hogrefe, Göttingen
Wittchen H-U, Jacobi F, Rehm J, Gustavsson A, Svensson M, Jönsson B, Olesen J, Allgulander C, Alonso J, Faravelli C (2011) The size and burden of mental disorders and other disorders of the brain in Europe 2010. Eur Neuropsychopharmacol 21:655–679
Wittchen H-U, Lachner G, Wunderlich U, Pfister H (1998) Test-retest reliability of the computerized DSM-IV version of the Munich-Composite International Diagnostic Interview (M-CIDI). Soc Psychiatry Psychiatr Epidemiol 33:568–578
Wittchen H-U, Pfister H (1997) DIA-X-Interviews: Manual für Screening-Verfahren und Interview; Interviewheft Längsschnittuntersuchung (DIA-X-Lifetime); Ergänzungsheft (DIA-X-Lifetime). In: Interviewheft Querschnittuntersuchung (DIA-X-12 Monate); Ergänzungsheft (DIA-X-12 Monate); PC-Programm zur Durchführung des Interviews (Längs- und Querschnittuntersuchung); Auswertungsprogramm. Swets & Zeitlinger, Frankfurt
Wittchen HU, Strehle J, Gerschler A, Volkert J, Dehoust MC, Sehner S, Wegscheider K, Ausìn B, Canuto A, Crawford M (2015) Measuring symptoms and diagnosing mental disorders in the elderly community: The test-retest reliability of the CIDI65+. Int J Methods Psychiatr Res 24:116–129
World Health Organization (ed) (1990) Composite International Diagnostic Interview (CIDI): (a) CIDI-interview (version 1.0), (b) CIDI-user manual, (c) CIDI-training manual (d) CIDI-computer programs. World Health Organization, Geneva
World Health Organization (ed) (1991) ICD-10. Mental and behavioral disorders (including disorders of psychopathological development): diagnostic guidelines, diagnostic criteria for research. World Health Organization, Geneva
Acknowledgements
SHIP is part of the Community Medicine Research net of the University of Greifswald, Germany, which is funded by the Federal Ministry of Education and Research (Grants no. 01ZZ9603, 01ZZ0103, and 01ZZ0403), the Ministry of Cultural Affairs and the Social Ministry of the Federal State of Mecklenburg-West Pomerania. Genome-wide data in SHIP have been supported by a joint grant from Siemens Healthineers, Erlangen, Germany, and the Federal State of Mecklenburg-West Pomerania. This work was also funded by the German Research Foundation (DFG: GR1912/5-1). Dr. Eva Asselmann was funded by a Junior Fellowship of the Alfried-Krupp-Wissenschaftskolleg of the University of Greifswald. Prof. Dr. Katja Beesdo-Baum was funded by grants of the Federal Ministry of Education and Research (Grants no 01ER1303 and 01ER1703).
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Asselmann, E., Beesdo-Baum, K., Hamm, A. et al. Lifetime and 12-month prevalence estimates for mental disorders in northeastern Germany: findings from the Study of Health in Pomerania. Eur Arch Psychiatry Clin Neurosci 269, 341–350 (2019). https://doi.org/10.1007/s00406-018-0911-5
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DOI: https://doi.org/10.1007/s00406-018-0911-5