Skip to main content
SpringerLink
Log in

Preoperative EABR evaluation of auditory pathway integrity in patients with different etiology and postoperative effect estimation

  • Otology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Objectives

To evaluate the effect of electrical auditory brainstem response (EABR) on the integrity evaluation of auditory pathway and the prediction of postoperative effect of cochlear implantation in patients with different etiology of hearing loss.

Methods

A total of 580 patients with neuropathic deafness who underwent cochlear implantation surgery from August 2011 to December 2020 were selected for EABR test. The preoperative EABR waveform was analyzed, and parameters such as V wave amplitude, threshold, latency and interval of each wave, and slope of V wave I/O curve were measured. Neural response telemetry (NRT) test was performed during MAP 1 month after operation, and C and T values of the machine were recorded.

Results

The total EABR extraction rate was 98.45% among 580 patients, including 100% for the normal structure group and enlarged vestibular aqueduct group (LVAS), 92.44% for other malformed group. The average threshold of V wave in patients with normal cochlear structure was significantly better than the malformation groups (p < 0.05). The total extraction rate of NRT was 78.62%, including 99.72% in the group with normal structure, 95.65% in the LVAS group, 1.85–88.24% in the group with other malformations, and 0% in the cochlear ossification group. The correlation analysis showed a statistically significant correlation between the average preoperative EABR threshold and the C value of NRT.

Conclusions

Preoperative EABR could evaluate the integrity of auditory conduction pathway of patients with cochlear implantation and predict the postoperative hearing rehabilitation effect.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

Availability of data and materials

All data generated or analysed during this study are included in this article. Further enquiries can be directed to the corresponding author.

References

  1. Layer N, Weglage A, Müller V et al (2022) The timecourse of multisensory speech processing in unilaterally stimulated cochlear implant users revealed by ERPs. Neuroimage Clin 34:102982

    Article  PubMed  PubMed Central  Google Scholar 

  2. Scheperle RA, Hajicek JJ (2020) Wideband acoustic immittance in cochlear implant recipients: reflectance and stapedial reflexes. Ear Hear 41(4):883–895

    Article  PubMed  PubMed Central  Google Scholar 

  3. Chen L, Zhang JG, Zhu HY et al (2023) Electrically evoked auditory brainstem responses in children fitted with hearing aids prior to cochlear implantation. Trends Hear 27:23312165221148850

    PubMed  PubMed Central  Google Scholar 

  4. Starr A, Brackman DE (1979) Brainstem potentials evoked by electrical stimulation of the cochlear in human subjects. Ann Otol Rhinol Laryngol 88(4 Pt 1):550–556

    Article  CAS  PubMed  Google Scholar 

  5. Gibson WP, Sanli H, Psarros C (2009) The use of intraoperative electrical auditory brainstem response to predict the speech perception outcome after cochlear implantation. Cochlear Implant Int 10(Suppl 1):53–57

    Article  Google Scholar 

  6. Wang B, Cao K, Wei C et al (2019) Evaluating auditory pathway by electrical auditory middle latency response and postoperative hearing rehabilitation. J Invest Surg 32(6):542–551

    Article  PubMed  Google Scholar 

  7. Wang B, Guo X, Cao K, Wei C, Gao Z, Wang S (2023) Evaluation of auditory pathway by EABR before cochlear implantation and the postoperative effect analysis. Eur Arch Otorhinolaryngol 280(1):105–114

    Article  PubMed  Google Scholar 

  8. Kileny PR, Zwolan TA, Zimmerman-Phillips S et al (1992) A comparison of round-window and transtympanic promontory electric stimulation in cochlear implant candidates. Ear Hear 13(5):294–299

    Article  CAS  PubMed  Google Scholar 

  9. Jeon JH, Bae MR, Song MH et al (2013) Relationship between electrically evoked auditory brainstem response and auditory performance after cochlear implant in patients with auditory neuropathy spectrum disorder. Otol Neurotol 34(7):1261–1266

    Article  PubMed  Google Scholar 

  10. Dutt SN, Kumar A, Mittal AA et al (2021) Cochlear implantation in auditory neuropathy spectrum disorders: role of transtympanic electrically evoked auditory brainstem responses and serial neural response telemetry. J LaryngolOtol 135(7):602–609

    Article  CAS  Google Scholar 

  11. Song MH, Bae MR, Kim HN et al (2010) Value of intracochlear electrically evoked auditory brainstem response after cochlear implantation in patients with narrow internal auditory canal. Laryngoscope 120(8):1625–1631

    Article  PubMed  Google Scholar 

  12. Wang Z, Liu Y, Wang L et al (2018) Characteristics of electrically evoked auditory brainstem responses in patients with cochlear nerve canal stenosis receiving cochlear implants. Int J Pediatr Otorhinolaryngol 104(1):98–103

    Article  PubMed  Google Scholar 

  13. Guedes MC, Brito Neto RV, Gomez MV et al (2005) Neural re- spons e telemetry measures in patient implanted with Nucle24. Braz J Otorhinolaryngol 71(5):660–667

    Article  PubMed  Google Scholar 

  14. Schvartz-Leyzac K, Zwolan T, Pfingst B (2021) Using the electrically-evoked compound action potential (ECAP) interphase gap effect to select electrode stimulation sites in cochlear implant users. Hear Res 406:1–13

    Article  Google Scholar 

  15. Maxwell AP, Mason SM, O’Donoghue GM (1999) Cochlear nerve aplasia: its importance in cochlear implantation. Am J Otol 20(3):335–337

    CAS  PubMed  Google Scholar 

  16. Lammers MJ, van Eijl RH, van Zanten GA (2015) Delayed auditory brainstem responses in prelingually deaf and late-implanted cochlear implant users. Assoc Res Otolaryngol 16(5):669–678

    Article  Google Scholar 

  17. Pfingst BE, Hughes AP, Colesa DJ (2015) Insertion trauma and recovery of function after cochlear implantation: evidence from objective functional measures. Hear Res 330(Pt A):98–105

    Article  PubMed  PubMed Central  Google Scholar 

  18. Nikolopoulos TP, Mason SM, O’Donoghue GM et al (1997) Electric auditory brain stem response in pediatric patients with cochlear implants. Am J Otol 18(6 Suppl):S120–S121

    CAS  PubMed  Google Scholar 

Download references

Funding

This study supported by National High Level Hospital Clinical Research Funding (No. 2022-PUMCH-A-031).

Author information

Author notes

  1. Bin Wang and Xiaohui Guo have contributed equally to this study.

Authors and Affiliations

  1. Department of Otolaryngology, Peking Union Medical College Hospital, No. 1 Shuaifuyuan, Dongcheng District, 100730, Beijing, China

    Bin Wang & Keli Cao

  2. Department of Ophthalmology, the Third Medical Center of PLA General Hospital, No. 28 Fuxing Road, Haidian District, 100853, Beijing, China

    Xiaohui Guo

  3. Department of Otolaryngology-Head and Neck Surgery, Peking University First Hospital, No. 8 Xishku Street, Xicheng District, 100034, Beijing, China

    Chaogang Wei

Authors
  1. Bin Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Xiaohui Guo
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Chaogang Wei
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Keli Cao
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

KC conceived of the study, and BW, XG and CW participated in its design and data analysis and statistics and Wang X helped to draft the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Keli Cao.

Ethics declarations

Conflict of interest

All of the authors had no any personal, financial, commercial, or academic conflicts of interest separately.

Ethical approval and consent to participate

This study was conducted in accordance with the Declaration of Helsinki and approved by the ethics committee of Peking Union Medical College Hospital. Written informed consent was obtained from all participants.

Consent for publication

Not applicable.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Wang, B., Guo, X., Wei, C. et al. Preoperative EABR evaluation of auditory pathway integrity in patients with different etiology and postoperative effect estimation. Eur Arch Otorhinolaryngol 281, 1185–1193 (2024). https://doi.org/10.1007/s00405-023-08198-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00405-023-08198-0

Keywords

Search

Navigation