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Exclusive endoscopic ossiculoplasty with autologous material: step-by-step procedure and functional results

  • Otology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Purpose

To describe the surgical procedure of exclusive endoscopic ossiculoplasty (EEO) with autologous grafts and evaluate audiological results, focusing on the advantages or drawbacks compared to the corresponding microscopic technique.

Methods

A retrospective review of consecutive adult and pediatric patients affected by chronic otitis media (COM) with or without cholesteatoma who underwent EEO was conducted. Only autologous ossiculoplasty was included in the study. The procedure was performed by experienced surgeons of our institution between November 2014 and September 2019. Hearing outcomes were evaluated using postoperative air–bone gap (ABG) and success rates in different subgroups of patients and different types of ossiculoplasty (OPL) were analyzed. Our results were finally compared with the existing literature regarding both microscopic and endoscopic ossicular chain reconstruction.

Results

In total, 74 endoscopic ossicular chain repair procedures performed within the study period met the inclusion criteria. Of these, 21 were pediatric patients (28%) and 53 were adults (72%). Surgical reconstruction procedures included 43 partial ossicular reconstructions (POR) and 31 total ossicular reconstructions (TOR). The postoperative ABG improved significantly compared to preoperative measurements, and the mean ABG closure was 7.85 dB HL (p = 0.00064). No statistically significant differences in audiological outcomes between TOR/POR techniques and pediatric/adult groups were found in our study cohort, with p values of 0.10 and 0.88, respectively.

Conclusions

At present, EEO can be considered a valid surgical option for re-establishing a functioning ossicular chain with acceptable hearing restoration in children and adults. Further reports in wider case series are required to confirm these results.

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Data availability

The data supporting the findings of this paper are available and can be provided if requested.

References

  1. Javia LR, Ruckenstein MJ (2006) Ossiculoplasty. Otolaryngol Clin North Am 39(6):1177–1189. https://doi.org/10.1016/j.otc.2006.08.010

    Article  PubMed  Google Scholar 

  2. Mudhol RS, Naragund AI, Shruthi VS (2013) Ossiculoplasty: revisited. Indian J Otolaryngol Head Neck Surg 65(Suppl 3):451–454. https://doi.org/10.1007/s12070-011-0472-7

    Article  CAS  PubMed  Google Scholar 

  3. Yu H, He Y, Ni Y, Wang Y, Lu N, Li H (2013) PORP vs TORP: a meta-analysis. Eur Arch Otorhinolaryngol 270(12):3005–3017. https://doi.org/10.1007/s00405-013-2388-1

    Article  PubMed  Google Scholar 

  4. McGee M, Hough JV (1999) Ossiculoplasty. Otolaryngol Clin North Am 32(3):471–488. https://doi.org/10.1016/s0030-6665(05)70146-8

    Article  CAS  PubMed  Google Scholar 

  5. Órfão T, Júlio S, Ramos JF, Dias CC, Silveira H, Santos M (2014) Audiometric outcome comparison between titanium prosthesis and molded autologous material. Otolaryngol Head Neck Surg 151(2):315–320. https://doi.org/10.1177/0194599814533074

    Article  PubMed  Google Scholar 

  6. Woods O, Fata FE, Saliba I (2009) Ossicular reconstruction: incus versus universal titanium prosthesis. Auris Nasus Larynx 36(4):387–392. https://doi.org/10.1016/j.anl.2008.10.001

    Article  PubMed  Google Scholar 

  7. Bartel R, Cruellas F, Hamdan M et al (2018) Hearing results after type III tympanoplasty: incus transposition versus PORP. A systematic review. Acta Otolaryngol 138(7):617–620. https://doi.org/10.1080/00016489.2018.1425901

    Article  PubMed  Google Scholar 

  8. Martins J, Silva H, Certal V, Amorim H, Carvalho C (2011) Osiculoplastia con prótesis de titanio [Ossiculoplasty with titanium prosthesis]. Acta Otorrinolaringol Esp 62(4):295–299. https://doi.org/10.1016/j.otorri.2011.02.008

    Article  PubMed  Google Scholar 

  9. Lim JH, Park JM, Han JJ, Kim SI, Park SY, Park SN (2018) Superiority of second stage ossiculoplasty. Otol Neurotol 39(10):1271–1276. https://doi.org/10.1097/MAO.0000000000002009

    Article  PubMed  Google Scholar 

  10. Tsetsos N, Vlachtsis K, Stavrakas M, Fyrmpas G (2021) Endoscopic versus microscopic ossiculoplasty in chronic otitis media: a systematic review of the literature. Eur Arch Otorhinolaryngol 278(4):917–923. https://doi.org/10.1007/s00405-020-06182-6

    Article  PubMed  Google Scholar 

  11. Bianconi L, Gazzini L, Laura E, De Rossi S, Conti A, Marchioni D (2020) Endoscopic stapedotomy: safety and audiological results in 150 patients. Eur Arch Otorhinolaryngol 277(1):85–92. https://doi.org/10.1007/s00405-019-05688-y. (Epub 2019 Oct 17)

    Article  PubMed  Google Scholar 

  12. Marchioni D, Gazzini L, De Rossi S, Di Maro F, Sacchetto L, Carner M, Bianconi L (2020) The management of tympanic membrane perforation with endoscopic type I tympanoplasty. Otol Neurotol 41(2):214–221. https://doi.org/10.1097/MAO.0000000000002465

    Article  PubMed  Google Scholar 

  13. Marchioni D, Rubini A, Gazzini L et al (2018) Complications in endoscopic ear surgery. Otol Neurotol 39(8):1012–1017. https://doi.org/10.1097/MAO.0000000000001933

    Article  PubMed  Google Scholar 

  14. Das A, Mitra S, Ghosh D, Sengupta A (2020) Endoscopic ossiculoplasty: Is there any edge over the microscopic technique? Laryngoscope 130(3):797–802. https://doi.org/10.1002/lary.28074

    Article  PubMed  Google Scholar 

  15. American Academy of Otolaryngology-Head and Neck Foundation, Inc. (1999) Committee on Hearing and Equilibrium guidelines for the diagnosis and evaluation of therapy in Menière’s disease. Otolaryngol Head Neck Surg 113(3):181–185. https://doi.org/10.1016/S0194-5998(95)70102-8

    Article  Google Scholar 

  16. Marchioni D, Rubini A, Nogueira JF et al (2018) Transcanal endoscopic approach to lesions of the suprageniculate ganglion fossa. Auris Nasus Larynx 45(1):57–65. https://doi.org/10.1016/j.anl.2017.03.006

    Article  PubMed  Google Scholar 

  17. Marchioni D, Alicandri-Ciufelli M, Grammatica A et al (2010) Lateral endoscopic approach to epitympanic diaphragm and Prussak’s space: a dissection study. Surg Radiol Anat 32(9):843–852. https://doi.org/10.1007/s00276-010-0691-8

    Article  PubMed  Google Scholar 

  18. Fernandez IJ, Fermi M, Ayache S et al (2021) Ossiculoplasty. In: Bonali M, Presutti L, Marchioni D (eds) Comparative atlas of endoscopic ear surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-47005-0_7

    Chapter  Google Scholar 

  19. Hall A, Rytzner C (1957) Stapedectomy and autotransplantation of ossicles. Acta Otolaryngol 47(4):318–324

    Article  CAS  PubMed  Google Scholar 

  20. Yung M, Hildmann H, Sudhoff HH (2006) Materials for ossicular chain reconstruction. In: Middle Ear Surgery, pp 55–61. https://doi.org/10.1007/978-3-540-47671-9_12

  21. Aldosari B, Thomassin J-M (2017) Audiological results of endoscopic surgical repair of the long process of incus. World J Otorhinolaryngol Head Neck Surg 3(3):148–152

    Article  PubMed  PubMed Central  Google Scholar 

  22. Potsangbam DS, Akoijam BA (2019) Endoscopic transcanal autologous cartilage ossiculoplasty. Indian J Otolaryngol Head Neck Surg 71(1):54–59

    Article  PubMed  Google Scholar 

  23. Presutti L, Anschuetz L, Rubini A et al (2018) The impact of the transcanal endoscopic approach and mastoid preservation on recurrence of primary acquired attic cholesteatoma. Otol Neurotol 39(4):445–450. https://doi.org/10.1097/MAO.0000000000001712

    Article  PubMed  Google Scholar 

  24. Das A, Mitra S, Ghosh D, Sengupta A (2020) Endoscopic versus microscopic management of attic cholesteatoma: a randomized controlled trial. Laryngoscope 130(10):2461–2466. https://doi.org/10.1002/lary.28446. (Epub 2019 Dec 9)

    Article  PubMed  Google Scholar 

  25. Marchioni D, Soloperto D, Villari D et al (2016) Stapes malformations: the contribute of the endoscopy for diagnosis and surgery. Eur Arch Otorhinolaryngol 273(7):1723–1729. https://doi.org/10.1007/s00405-015-3743-1. (Epub 2015 Aug 8)

    Article  PubMed  Google Scholar 

  26. Chung J, Kang JY, Kim MS, Kim B, Choi JW (2020) Microscopic vs endoscopic ear surgery for congenital ossicular anomaly. Otolaryngol Head Neck Surg 162(4):548–553. https://doi.org/10.1177/0194599819900489. (Epub 2020 Jan 21)

    Article  PubMed  Google Scholar 

  27. Dixon PR, James AL (2020) Evaluation of residual disease following transcanal totally endoscopic vs postauricular surgery among children with middle ear and attic cholesteatoma. JAMA Otolaryngol Head Neck Surg 146(5):408–413. https://doi.org/10.1001/jamaoto.2020.0001

    Article  PubMed  Google Scholar 

  28. Iannella G, De Vincentiis M, Greco A et al (2019) Endoscopic approach in second stage ossicular chain reconstruction. Am J Otolaryngol 40(5):735–742. https://doi.org/10.1016/j.amjoto.2019.07.004

    Article  PubMed  Google Scholar 

  29. Marchioni D, Soloperto D, Rubini A et al (2015) Endoscopic exclusive transcanal approach to the tympanic cavity cholesteatoma in pediatric patients: our experience. Int J Pediatr Otorhinolaryngol 79(3):316–322. https://doi.org/10.1016/j.ijporl.2014.12.008. (Epub 2015 Jan 7)

    Article  PubMed  Google Scholar 

  30. O’Reilly RC, Cass SP, Hirsch BE, Kamerer DB, Bernat RA, Poznanovic SP (2005) Ossiculoplasty using incus interposition: hearing results and analysis of the middle ear risk index. Otol Neurotol 1:853–858

    Article  Google Scholar 

  31. Mulazimoglu S, Saxby A, Schlegel C et al (2017) Titanium incus interposition ossiculoplasty: audiological outcomes and extrusion rates. Eur Arch Otorhinolaryngol 274:3303–3310. https://doi.org/10.1007/s00405-017-4634-4

    Article  PubMed  Google Scholar 

  32. House JW, Teufert KB (2001) Extrusion rates and hearing results in ossicular reconstruction. Otolaryngol Head Neck Surg 125(3):135–141

    Article  CAS  PubMed  Google Scholar 

  33. Vrabec JT, Stierman K, Grady JJ (2002) Hydroxyapatite prosthesis extrusion. Otol Neurotol 23(5):653–656

    Article  PubMed  Google Scholar 

  34. Kortebein S, Russomando AC, Greda D, Cooper M, Ledbetter L, Kaylie D (2023) Ossicular chain reconstruction with titanium prostheses: a systematic review and meta-analysis. Otol Neurotol 44(2):107–114

    Article  PubMed  Google Scholar 

  35. Amith N, Rs M (2017) Autologous incus versus titanium partial ossicular replacement prosthesis in reconstruction of Austin type A ossicular defects: a prospective randomised clinical trial. J Laryngol Otol 131(5):391–398. https://doi.org/10.1017/S0022215117000251

    Article  PubMed  Google Scholar 

  36. Alaani A, Raut VV (2010) Kurz titanium prosthesis ossiculoplasty—follow-up statistical analysis of factors affecting one year hearing results. Auris Nasus Larynx 37:150–154

    Article  CAS  PubMed  Google Scholar 

  37. Gardner EK, Jackson CG, Kaylie DM (2004) Results with titanium ossicular reconstruction prostheses. Laryngoscope 114:65–70

    Article  CAS  PubMed  Google Scholar 

  38. Vassbotn FS, Moller P, Silvola J (2007) Short-term results using Kurz titanium ossicular implants. Eur Arch Otorhinolaryngol 264:21–25

    Article  PubMed  Google Scholar 

  39. Mardassi A, Deveze A, Sanjuan M (2011) Titanium ossicular chain replacement prostheses: prognostic factors and preliminary functional results. Eur Ann Otorhinolaryngol Head Neck Dis 128:53–58

    Article  CAS  PubMed  Google Scholar 

  40. Geyer G, Rocker J (2002) Results after rebuilding the ossicular chain using the autogenous incus, ionomer-cement-and titanium implants (tympanoplasty type III). Laryngorhinootologie 81:164–170

    Article  CAS  PubMed  Google Scholar 

  41. Zhang LC, Zhang TY, Dai PD et al (2011) Titanium versus non-titanium prostheses in ossiculoplasty: a meta-analysis. Acta Otolaryngol 131:708–715

    Article  CAS  PubMed  Google Scholar 

  42. Filosa B, Previtero G, Novia G, Trusio A, Malafronte G (2019) Partial ossiculoplasty: malafronte’s double cartilage block versus incus. Otol Neurotol 40:344–350. https://doi.org/10.1097/MAO.0000000000002137

    Article  PubMed  Google Scholar 

  43. Baker AB, O’Connell BP, Nguyen SA, Lambert PR (2015) Ossiculoplasty with titanium prostheses in patients with intact stapes: comparison of TORP versus PORP. Otol Neurotol 36(10):1676–1682

    Article  PubMed  Google Scholar 

  44. Weiss NM, Ha VY, Großmann W, Oberhoffner T, Schraven SP, Mlynski RA (2020) Comparison of total and partial ossicular replacement prostheses in patients with an intact stapes suprastructure. Laryngoscope 130(3):768–775

    Article  PubMed  Google Scholar 

  45. McGill TJ, Merchant S, Healy GB, Friedman EM (1991) Congenital cholesteatoma of the middle ear in children: a clinical and histopathological report. Laryngoscope 101(6 Pt 1):606–613

    CAS  PubMed  Google Scholar 

  46. Marchioni D, Gazzini L, Bisi N, Barillari M, Rubini A (2021) Subcochlear canaliculus patterns in the pediatric and adult population: radiological findings and surgical implications. Surg Radiol Anat 43(8):1285–1290. https://doi.org/10.1007/s00276-021-02709-6. (Epub 2021 Feb 20)

    Article  PubMed  Google Scholar 

  47. Dornelles C, Da Costa SS, Meurer L, Schweiger C (2005) Some considerations about acquired adult and pediatric cholesteatomas. Braz J Otorhinolaryngol 71(4):536–545

    Article  PubMed  Google Scholar 

  48. Edelstein DR, Parisier SC, Chute P et al (1988) Cholesteatoma in the pediatric age group. Ann Otol Rhinol Laryngol 97(1):23–29

    Article  CAS  PubMed  Google Scholar 

  49. Caloway CL, Basonbul RA, Ronner EA et al (2020) Pediatric endoscopic ossiculoplasty following surgery for chronic ear disease. Laryngoscope 130(12):2896-2899. https://doi.org/10.1002/lary.28526

    Article  PubMed  Google Scholar 

  50. Özdamar K, Şen A (2020) The effect of age on ossiculoplasty results: a retrospective evaluation of 60 cases. Auris Nasus Larynx 47(2):209–214. https://doi.org/10.1016/j.anl.2019.08.006. (Epub 2019 Sep 7)

    Article  PubMed  Google Scholar 

  51. Zakzouk A, Bonmardion N, Bouchetemble P, Lerosey Y, Marie JP (2015) Titanium prosthesis or autologous incus for total ossicular reconstruction in the absence of the stapes suprastructure and presence of mobile footplate. Eur Arch Otorhinolaryngol 272(10):2653–2657

    Article  PubMed  Google Scholar 

  52. Yawn RJ, Hunter JB, O’Connell BP et al (2017) Audiometric outcomes following endoscopic ossicular chain reconstruction. Otol Neurotol 38(9):1296–1300

    Article  PubMed  Google Scholar 

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Correspondence to Raffaele Cerullo.

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Soloperto, D., Laura, E., Gazzini, L. et al. Exclusive endoscopic ossiculoplasty with autologous material: step-by-step procedure and functional results. Eur Arch Otorhinolaryngol 280, 4869–4878 (2023). https://doi.org/10.1007/s00405-023-08005-w

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