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Investigating factors influencing post-operative growth in pre-pubertal children after adenotonsillectomy

  • Rhinology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Purpose

To check the change in growth-for-age after adenotonsillectomy in pre-pubertal children and investigate the affecting factors.

Methods

Two hundred and six pediatric patients who underwent adenotonsillectomy by a single surgeon between January 2011 and December 2014 were included for the retrospective cohort study. The z-scores of height-, weight-, and body mass index (BMI)-for-age were measured before adenotonsillectomy and 1 year after the operation. The Korean version of the obstructive sleep apnea-18 questionnaire (OSA-18), symptom questionnaire, physical examinations, demographic data, and pre-operative z-scores were used to analyze the factors affecting z-score change.

Results

Among 206 pediatric patients, 167 patients were normal growth; 19 were undergrowth; and 20 were obese. After the operation, height, weight, and BMI z-scores all increased both in 167 normal-growth patients and 19 undergrowth patients (p value < 0.05). However, in 20 obese patients, only height z-score significantly increased (p value = 0.028). The multiple regression test showed that the sleep disturbance domain of OSA-18 was positively correlated with height z-score change (p value = 0.041), and age was negatively correlated with weight z-score change (p value = 0.016). Pre-operative BMI z-score was negatively correlated (p value = 0.019) and adenoid grade was positively correlated (p value = 0.023) with BMI z-score change.

Conclusions

These findings suggest that adenotonsillectomy may positively affect growth in pre-pubertal children, without undesirable weight gain. Additionally, the sleep disturbance domain of OSA-18 may play a role in predicting post-operative height increase in pre-pubertal children.

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Availability of data and materials

The data that support the findings of this study are available from the corresponding author upon reasonable request.

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Authors and Affiliations

  1. Department of Otorhinolaryngology, Seoul National University College of Medicine, Seoul National University Hospital, 101 Daehak-Ro, Jongno-Gu, Seoul, 03080, Korea

    Seung Cheol Han, Seung Koo Yang, Sang-Yoon Han, Chae-Seo Rhee & Doo Hee Han

  2. Graduate School of Immunology, Seoul National University College of Medicine, Seoul, Korea

    Chae-Seo Rhee

  3. Institute of Allergy and Clinical Immunology and Sensory Organ Research Institute, Seoul National University Biomedical Research Center, Seoul, Korea

    Chae-Seo Rhee

  4. Medical Research Collaborating Center, Seoul National University Hospital, Seoul, Korea

    Yunhee Choi

  5. Department of Pediatrics, Seoul National University College of Medicine, Seoul National University Children’s Hospital, 101 Daehak-Ro, Jongno-Gu, Seoul, 03080, Korea

    Choong Ho Shin & Yun Jeong Lee

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  1. Seung Cheol Han
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Correspondence to Yun Jeong Lee or Doo Hee Han.

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Han, S.C., Yang, S.K., Han, SY. et al. Investigating factors influencing post-operative growth in pre-pubertal children after adenotonsillectomy. Eur Arch Otorhinolaryngol 280, 2841–2848 (2023). https://doi.org/10.1007/s00405-022-07817-6

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  • DOI: https://doi.org/10.1007/s00405-022-07817-6

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