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Can polysomnography be replaced by ApneaGraph200 for OSA diagnosis? A protocol for systematic review and meta-analysis

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European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Background

It is yet unknown if the ApneaGraph200 system can replace the Polysomnography system (PSG), which is now the gold standard for obstructive sleep apnea (OSA) diagnosis. We performed a meta-analysis to evaluate the difference in apnea hypopnea index and lowest oxygen saturation levels between the AG200 system and PSG system.

Methods

Utilizing PubMed, Elsevier, Wanfang, and China National Knowledge Internet (CNKI), a thorough literature search was carried out. Eligible studies contrasting the AG200 system and the PSG system were found by two separate researchers. Review Manager (version 5.3) was adopted for data synthesis.

Results

The meta-analysis A pooled the comparison of AHI between the AG and PSG groups, and included seven studies involving a total of 419 participants, which revealed that there was a significant difference in AHI between the above two diagnostic methods (standard mean difference (SMD) = − 0.19, 95% confidence interval (CI) = − 0.32 to − 0.05, P = 0.008). As a supplementary, meta-analysis B pooled the comparison of lowest oxygen saturation between the AG and PSG groups and included five studies involving a total of 224 participants. It revealed that there was no significant difference between the AG group and the PSG group (SMD = 0.09, 95% CI − 0.24 to 0.43, P = 0.58).

Conclusion

The ApneaGraph200 system can be used for the initial screening of OSA patients, but it is not a complete alternative to polysomnography for the diagnosis and severity of the OSA condition.

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Availability of data and materials

All data generated or analyzed in this study are included in this published article.

Abbreviations

AHI:

Apnea–hypopnea index

BMI:

Body mass index

CI:

Confidence interval

OSA:

Obstructive sleep apnea

PSG:

Polysomnography

AG:

ApneaGraph200

DISE:

Drug-induced sleep endoscopy

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Authors and Affiliations

  1. Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China

    Yuzhang Chen & Xun Niu

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  1. Yuzhang Chen
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  2. Xun Niu
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Contributions

YC, designed study, collected data, analyzed data, wrote article; XN, designed study, revised article.

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Correspondence to Xun Niu.

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Chen, Y., Niu, X. Can polysomnography be replaced by ApneaGraph200 for OSA diagnosis? A protocol for systematic review and meta-analysis. Eur Arch Otorhinolaryngol 280, 2065–2072 (2023). https://doi.org/10.1007/s00405-022-07815-8

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  • DOI: https://doi.org/10.1007/s00405-022-07815-8

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