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Table 2 Differences in RAND-36 dimensions between assessments at 2 years and 5 years after free flap surgery for cancer of the head and neck

From: Quality of life in head and neck cancer patients at 5 years after free flap reconstruction: a significant decline during the follow-up

Dimension 5-year value Baseline Difference P value General value Number of responders answering below age-adjusted reference
Physical functioning 68.0 (27.0) 86.1 (21.8) − 18.0 (− 25.5 to − 10.5) < 0.001 84.9 (22.1) 12 (35.7)
Role functioning physical 58.3 (41.6) 76.4 (27.8) − 18.1 (34.3 to − 1.8) 0.031 74.8 (35.5) 10 (35.7)
Role functioning emotional 65.4 (42.8) 79.0 (30.9) − 13.6 (31.6 to − 4.4) 0.133 75.0 (36.4) 13 (16.4)
Energy/fatigue 60.4 (23.9) 78.9 (14.9) − 18.5 (25.7 to − 11.3)  < 0.001 64.0 (22.4) 10 (35.7)
Emotional well-being 75.1 (17.5) 85.8 (11.4) − 10.7 (17.3 to − 4.0) 0.003 73.7 (19.7) 11 (39.3)
Social functioning 70.1 (26.9) 85.3 (18.3) − 15.2 (27.2 to − 3.1) 0.015 82.1 (23.2) 16 (57.1)
Pain 66.6 (25.5) 81.1 (19.3) − 14.5 (− 23.9 to − 5.0) 0.004 76.2 (24.0) 13 (46.4)
General health 52.2 (21.8) 63.1 (19.9) − 10.9 (− 17.9 to 3.9) 0.003 65.0 (19.8) 10 (35.7)