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Hearing recovery after surgical resection of non-vestibular schwannoma cerebellopontine angle tumors

  • Otology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Purpose

Post-operative outcomes for hearing after resection surgery to remove cerebellopontine angle (CPA) tumors other than vestibular schwannomas (VS) are not well understood. This study presents a series of patients with significant post-operative hearing recovery, trying to define the incidence among all patients operated on for removal of non-VS CPA tumors.

Methods

This is a retrospective observational case series of 8 patients among 69 operated on for removal of non-VS CPA tumors between 2012 and 2020. All patients had pre- and post-operative hearing measurement with pure-tone average (PTA) and speech discrimination score (SDS), according to the American Academy of Otolaryngology-Head and Neck Surgery recommendations, auditory brainstem response (ABR) measurements and imaging.

Results

Six meningiomas and two lower cranial nerve schwannomas operated on with a retrosigmoid approach were included for analysis. The mean pre-operative PTA and SDS were 58 ± 20.7 dB and 13 ± 17.5%, respectively. All patients had pre-operative class D hearing and asynchronous ABRs. They all showed significant hearing recovery, with an improvement of 36 ± 22.2 dB (p = 0.0025) and 85 ± 16.9% (p = 0.0001) in PTA and SDS, respectively, with mean follow-up of 21 ± 23.5 months. Seven patients recovered to a class A hearing level and one patient to class B. The ABRs became synchronous for three patients. The incidence of auditory recovery was 13% for patients operated on with a conservative approach (n = 60).

Conclusion

A significant post-operative improvement in hearing could be a reasonable expectation in non-VS tumors extending into the CPA and a retrosigmoid approach should always be considered regardless of pre-operative hearing status.

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Code availability

https://doi.org/10.6084/m9.figshare.14057975.

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Authors and Affiliations

  1. Groupe Hospitalo-Universitaire Pitié-Salpêtrière, Département d’Oto-Rhino-Laryngologie, APHP Sorbonne Université, 47-83 boulevard de l’Hôpital, 75651, Paris Cedex 13, France

    Naira Mkrtchyan, Lauranne Alciato, Daniele Bernardeschi, Olivier Sterkers, Mustapha Smail & Ghizlene Lahlou

  2. Institut de l’Audition/Institut Pasteur, Équipe TGTD «Technologies and Gene Therapy for Deafness», Paris, France

    Lauranne Alciato, Olivier Sterkers & Ghizlene Lahlou

  3. Groupe Hospitalo-Universitaire Pitié-Salpêtrière, Département de Neurochirurgie, APHP Sorbonne Université, Paris, France

    Michel Kalamarides

  4. Groupe Hospitalo-Universitaire Pitié-Salpêtrière, Département de Neurologie, APHP Sorbonne Université, Paris, France

    Isabelle Bernat

  5. Groupe Hospitalo-Universitaire Pitié-Salpêtrière, Département de Neuroradiologie, APHP Sorbonne Université, Paris, France

    Nadya Pyatigorskaya

Authors
  1. Naira Mkrtchyan
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  2. Lauranne Alciato
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Correspondence to Ghizlene Lahlou.

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Mkrtchyan, N., Alciato, L., Kalamarides, M. et al. Hearing recovery after surgical resection of non-vestibular schwannoma cerebellopontine angle tumors. Eur Arch Otorhinolaryngol 279, 2373–2382 (2022). https://doi.org/10.1007/s00405-021-06956-6

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  • DOI: https://doi.org/10.1007/s00405-021-06956-6

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