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Short-term outcome of transcutaneous glucocorticoid injection for laryngeal contact granuloma in females

  • Laryngology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Objective

To evaluate the short-term efficacy of transcutaneous glucocorticoid injection for laryngeal contact granuloma in females.

Methods

A total of 14 female patients with laryngeal contact granuloma treated in our outpatient department from November 2017 to January 2020 were included in the study. Inspiratory-phase laryngoscopy images were collected before treatment and 1 month after each injection, and the lesion size was measured and evaluated with ImageJ software.

Results

Two patients achieved complete remission after one injection, with a percent reduction of 100%. After two injections, 4 patients achieved complete remission, with a percent reduction ranging from 96% to 100%. After 3 injections, 4 patients achieved complete remission (including one patient with bilateral lesions), and the percent reduction ranged from 95% to 100%. Three patients achieved incomplete remission, with a percent reduction of 46%, 55%, and 81%, respectively. In one case, there was no remission, and the granuloma increased in size after treatment.

Conclusion

In women with laryngeal contact granuloma, transcutaneous glucocorticoid injection therapy can quickly resolve the granuloma in a short period.

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Authors and Affiliations

  1. Department of Otolaryngology Head and Neck Surgery, Sixth Medical Center of PLA General Hospital; College of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital; National Clinical Research Center for Otolaryngologic Diseases, Beijing, China

    Ran Zhang, Jinrang Li, Qian Nie, Mukun Wu & Yuanyuan Jia

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  1. Ran Zhang
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  2. Jinrang Li
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  3. Qian Nie
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  4. Mukun Wu
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  5. Yuanyuan Jia
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Correspondence to Jinrang Li.

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Zhang, R., Li, J., Nie, Q. et al. Short-term outcome of transcutaneous glucocorticoid injection for laryngeal contact granuloma in females. Eur Arch Otorhinolaryngol 278, 1499–1504 (2021). https://doi.org/10.1007/s00405-020-06595-3

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  • DOI: https://doi.org/10.1007/s00405-020-06595-3

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