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Stapes surgery in osteogenesis imperfecta: retrospective analysis of 18 operated ears

  • Otology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Purpose

To evaluate short and long term results of stapes surgery in patients with osteogenesis imperfecta (OI),

Methods

Retrospective case series of 18 primary stapes surgeries performed on 11 hearing-impaired OI patients with evidence of stapes fixation, in a Tertiary referral center. We analysed pre-operative and post-operative hearing results at 1 month and at least 1 year

Results

The main operative findings were stapes fixation, thickened footplate and fragile or fractured stapes crura. No revision surgery was necessary.

Hearing improvement was achieved in 94% of the cases. We obtained an air–bone gap closure to within 10 dB in 46% of the cases and to within 15 dB in 92% of the cases at 1-year follow-up.

The mean hearing gain in air conduction (at 0.5, 1, 2 and 4 kHz) was 18.4 dB at 1 month and 22.4 dB at 1 year.

Conclusion

Stapes surgery in OI gives good results with few complications in our series. A hearing gain is often obtained in spite of the sensorineural hearing loss caused by the natural progression of the disease

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Availability of data and materials

The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request.

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Funding

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Authors and Affiliations

  1. Department of Otorhinolaryngology-Head and Neck Surgery and Audiophonology, Eure-Seine Hospital, Evreux, France

    M. Hijazi

  2. Department of Biostatistics, Rouen University Hospital, Rouen, France

    S. D. Mihailescu

  3. CIRCE NEV (Innovation, Clinical Research and Educational Unit Normandie Evreux Vernon), Eure-Seine Hospital, Evreux, France

    S. D. Mihailescu

  4. Department of Radiology, University Hospital, Rouen, France

    J. Horion

  5. Department of Genetics and Reference Center for Developmental Disorders, Normandy Center for Genomic and Personalized Medicine, UNIROUEN, Normandie Univ, Inserm U1245 and Rouen University Hospital, Rouen, France

    A. Goldenberg

  6. Department of Otorhinolaryngology-Head and Neck Surgery and Audiophonology, University Hospital, Rouen, France

    J. P. Marie

Authors
  1. M. Hijazi
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  2. S. D. Mihailescu
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  3. J. Horion
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  4. A. Goldenberg
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  5. J. P. Marie
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Corresponding author

Correspondence to M. Hijazi.

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Conflicts of interest

The authors declare that they have no conflicts of interest

Ethics approval

This is a retrospective observational study. The Research Ethics Committee of our university hospital has confirmed that no ethical approval was required. Archival patient’s data were anonymized.

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Hijazi, M., Mihailescu, S.D., Horion, J. et al. Stapes surgery in osteogenesis imperfecta: retrospective analysis of 18 operated ears. Eur Arch Otorhinolaryngol 278, 4697–4705 (2021). https://doi.org/10.1007/s00405-020-06581-9

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  • DOI: https://doi.org/10.1007/s00405-020-06581-9

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