Abstract
Background
Outcomes of surgical management of obstructive sleep apnea–hypopnea syndrome (OSAHS) can be difficult to predict preoperatively.
Aims/objectives
To study the effect of applying traction to the velum during drug-induced sleep endoscopy (DISE) in OSAHS patients, and to describe the use of traction velum in predicting surgical success.
Materials and methods
41 adult surgical patients with OSA (Friedman tongue position II and III) were evaluated by DISE. All patients subsequently underwent velopharyngeal surgery in the form of uvulopalatopharyngoplasty with tonsillectomy plus barbed reposition pharyngoplasty.
Results
Surgical responders (n = 26, 63.4%) and nonresponders (n = 15, 36.6%) demonstrated no significant differences with regard to preoperative AHI, age, sex, body mass index, and mean/lowest O2 saturation. Responders had a marked decrease in desaturation events (2.96 vs 0.03, p < 0.001) and percentage change in number of desaturation events before/after traction velum (56.7 vs 4.5, p < 0.001). Regression analysis revealed that reduction in mean desaturation events, with traction velum, by a percentage > 26.8% (odds ratio [OR] 1.046; 95% confidence interval [CI] 1.018–1.075; p = 0.001) was the only independent predictor of surgery success.
Conclusions and significance
OSAHS patients’ velopharyngeal surgical outcome can be predicted by measuring the percentage change in the number of oxygen desaturation events before and after traction velum in DISE.
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References
Malhotra A, White DP (2002) Obstructive sleep apnoea. Lancet 360(9328):237–245
Peppard PE, Young T, Palta M et al (2000) Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med 342(19):1378–1384
Shahar E, Whitney CW, Redline S et al (2001) Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study. Am J Respir Crit Care Med 163(1):19–25
Sommer UJ, Heiser C, Gahleitner C et al (2016) Tonsillectomy with uvulopalatopharyngoplasty in obstructive sleep apnea. Dtsch Arztebl Int. 113(1–02):1–8
Chi JC, Chiang RP, Chou TY et al (2015) The role of lateral pharyngoplasty in obstructive sleep apnea syndrome. Eur Arch Otorhinolaryngol 272(2):489–496
Dizdar D, Civelek S, Calis ZA et al (2015) Comparative analysis of lateral pharyngoplasty and uvulopalatopharyngoplasty techniques with polisomnography and epworth sleepiness scales. J Craniofac Surg. 26(7):e647–e651
Cahali MB, Formigoni GG, Gebrim EM et al (2004) Lateral pharyngoplasty versus uvulopalatopharyngoplasty: a clinical, polysomnographic and computed tomography measurement comparison. Sleep 27(5):942–950
De Vito A, Llatas MC, Vanni A et al (2014) European position paper on drug-induced sedation endoscopy (DISE). Sleep and Breathing. 18(3):453–465
Vicini C, Hendawy E, Campanini A et al (2015) Barbed reposition pharyngoplasty (BRP) for OSAHS: a feasibility, safety, efficacy and teachability pilot study. “We are on the giant’s shoulders”. Eur Arch Otorhinolaryngol 272(10):3065–3070
Berry RB, Budhiraja R, Gottlieb DJ et al (2012) Rules for scoring respiratory events in sleep: update of the 2007 AASM manual for the scoring of sleep and associated events. J Clin Sleep Med 8(05):597–619
De Vito A, Carrasco Llatas M, Ravesloot MJ et al (2018) European position paper on drug-induced sleep endoscopy: 2017 Update. Clin Otolaryngol 43(6):1541–1552
Kezirian EJ, Hohenhorst W, de Vries N (2011) Drug-induced sleep endoscopy: the VOTE classification. Eur Arch Otorhinolaryngol 268(8):1233–1236
Gleadhill IC, Schwartz AR, Schubert N et al (1991) Upper airway collapsibility in snorers and in patients with obstructive hypopnea and apnea. Am Rev Respir Dis 143(6):1300–1303
Sher AE, Schechtman KB, Piccirillo JF (1996) The efficacy of surgical modifications of the upper airway in adults with obstructive sleep apnea syndrome. Sleep 19(2):156–177
Malhotra A, Fogel RB, Edwards JK et al (2000) Local mechanisms drive genioglossus activation in obstructive sleep apnea. Am J Respir Crit Care Med 161(5):1746–1749
Onal E, Lopata M, Oconnor T (1981) Diaphragmatic and genioglossal electromyogram responses to CO2 rebreathing in humans. J Appl Physiol 50(5):1052–1055
Sforza E, Petiau C, Weiss T et al (1999) Pharyngeal critical pressure in patients with obstructive sleep apnea syndrome: clinical implications. Am J Respir Crit Care Med 159(1):149–157
Smith PL, Wise RA, Gold AR et al (1988) Upper airway pressure-flow relationships in obstructive sleep apnea. J Appl Physiol 64(2):789–795
Schwartz AR, Smith PL, Wise RA et al (1988) Induction of upper airway occlusion in sleeping individuals with subatmospheric nasal pressure. J Appl Physiol 64(2):535–542
Haponik EF, Smith PL, Bohlman ME et al (1983) Computerized tomography in obstructive sleep apnea: correlation of airway size with physiology during sleep and wakefulness. Am Rev Respir Dis 127(2):221–226
Schwab RJ, Gupta KB, Gefter WB et al (1995) Upper airway and soft tissue anatomy in normal subjects and patients with sleep-disordered breathing. Significance of the lateral pharyngeal walls. Am J Respir Crit Care Med 152(5):1673–1689
Chen H, Li X, Ye H et al (2012) Value of tonsillectomy in patient with obstructive sleep apnea hypopnea syndrome with Friedman staging I. Chin J Otorhinolaryngol Head Neck Surg 47(2):107–111
Friedman M, Ibrahim H, Bass L (2002) Clinical staging for sleep-disordered breathing. Otolaryngol Head Neck Surg 127(1):13–21
Friedman M, Ibrahim H, Joseph NJ (2004) Staging of obstructive sleep apnea/hypopnea syndrome: a guide to appropriate treatment. Laryngoscope. 114(3):454–459
Yi HL, Yin SK, Zhang YJ et al (2009) Z-palatopharyngoplasty for obstructive sleep apnea/hypopnea syndrome. Otolaryngol Head Neck Surg 140(5):640–645
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Zhu, M., Gong, S., Ye, J. et al. Predicting outcome of velopharyngeal surgery in drug-induced sleep endoscopy by traction velum. Eur Arch Otorhinolaryngol 278, 821–826 (2021). https://doi.org/10.1007/s00405-020-06292-1
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DOI: https://doi.org/10.1007/s00405-020-06292-1