Skip to main content

Advertisement

Log in

Closing of large pharyngostomes with free flaps and proposal of a new classification

  • Head and Neck
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Purpose

Large pharyngocutaneous fistulas or pharyngostomes are difficult complications to solve, which generate high morbidity and mortality, a poor quality of life and an increase in health costs. Its management must be comprehensive according to general, local and regional factors. We review our experience in treating these pharyngostomes with free flaps.

Methods

Retrospective study analyzing the results of the reconstruction of 50 patients using free flaps during the period 1991–2019. We exclude patients who required free-flap reconstruction due to primary tumor or those who resolved in other ways. The different types of reconstruction were classified into three types.

Results

The 86% (43) were men, and the mean age was 57 years (25–76). In 48% (24/50) the flaps performed were anterolateral thigh (ALT), in 24% (12/50) forearm, in 22% (11/50) parascapular, in 4% (2/50) jejunum and in 2% (1/50) ulnar. A salivary by-pass was placed in 74% (37/50) of the cases. Four cases (8%) presented flap necrosis and two patients died due to treatment. In 86% (43/50) there was some type of complication and 34% (17/50) required surgical revision. 94% (45/48) were able to reintroduce oral feeding.

Conclusion

According to our experience, we proposed a regardless size classification: type 1 when only a mucous closure (pharynx) are required (6%), type 2 exclusively skin for cutaneous coverage (10%) and mixed type 3 (mucous and skin) (84%). The treatment of large pharyngostomes with free flaps, despite its complexity, is in our experience the best option for its management.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Rodrigo JP, López F, Llorente JL, Álvarez-Marcos C, Suárez C (2015) Results of total laryngectomy as treatment for locally advanced laryngeal cancer in the organ-preservation era. Acta Otorrinolaringol Esp 66(3):132–138

    Article  Google Scholar 

  2. Klozar J, Cada Z, Koslabova E (2012) Complications of total laryngectomy in the era of chemoradiation. Eur Arch Oto-Rhino-Laryngol 269(1):289–293

    Article  Google Scholar 

  3. Casasayas M, Sansa A, García-Lorenzo J, López M, Orús C, Peláez X et al (2019) Pharyngocutaneous fistula after total laryngectomy: multivariate analysis of risk factors and a severity-based classification proposal. Eur Arch Oto-Rhino-Laryngol 276(1):143–151

    Article  Google Scholar 

  4. van Bokhorst-de van der Schueren MA, van Leeuwen PA, Sauerwein HP, Kuik DJ, Snow GB, Quak JJ (1997) Assessment of malnutrition parameters in head and neck cancer and their relation to postoperative complications. Head Neck 19(5):419–425

    Article  Google Scholar 

  5. Sumarroca A, Rodríguez-Bauzà E, Lop-Gros J, García J, López M, Quer M et al (2019) Repair of post-laryngectomy pharyngocutaneous fistulas using a pectoralis major flap. Braz J Otorhinolaryngol 85(3):351–356

    Article  Google Scholar 

  6. Sevilla García MA, Suárez Fente V, Rodrigo Tapia JP, Llorente Pendás JL (2006) Montgomery salivary bypass tube: a simple solution for pharyngocutaneous fistulas. Acta Otorrinolaringol Esp 57(10):467–470

    Article  Google Scholar 

  7. Guthrie RH, Kovachev D, Schwager RG (1974) Pharyngostome repairs. Surg Clin North Am 54(4):767–786

    Article  Google Scholar 

  8. Ragbir M, Brown JS, Mehanna H (2016) Reconstructive considerations in head and neck surgical oncology: United Kingdom National Multidisciplinary Guidelines. J Laryngol Otol 130(S2):S191–S197

    Article  CAS  Google Scholar 

  9. Pegan A, Rašić I, Košec A, Solter D, Vagić D, Bedeković V et al (2018) Type II hypopharyngeal defect reconstruction-a single institution experience. Acta Clin Croat 57(4):673–680

    PubMed  PubMed Central  Google Scholar 

  10. Hyun D-J, Joo Y-H, Kim M-S (2017) Impact of pre-operative body mass index in head and neck cancer patients undergoing microvascular reconstruction. J Laryngol Otol 131(11):972–976

    Article  Google Scholar 

  11. Formeister EJ, Sean Alemi A, El-Sayed I, George JR, Ha P, Daniel Knott P et al (2018) Shorter interval between radiation therapy and salvage laryngopharyngeal surgery increases complication rates following microvascular free tissue transfer. Am J Otolaryngol 39(5):548–552

    Article  Google Scholar 

  12. Llorente JL, López F, Suárez V, Fueyo Á, Carnero S, Martín C et al (2014) Free flap reconstruction in the head and neck. Indications, technical aspects and outcomes. Acta Otorrinolaringol Esp 65(1):33–42

    Article  Google Scholar 

  13. López F, Obeso S, Camporro D, Fueyo Á, Suárez C, Llorente JL (2013) Outcomes following pharyngolaryngectomy with fasciocutaneous free flap reconstruction and salivary bypass tube. Laryngoscope 123(3):591–596

    Article  Google Scholar 

  14. Haidar YM, Tripathi PB, Tjoa T, Walia S, Zhang L, Chen Y et al (2018) Antibiotic prophylaxis in clean-contaminated head and neck cases with microvascular free flap reconstruction: a systematic review and meta-analysis. Head Neck 40(2):417–427

    Article  Google Scholar 

  15. Morinière S, Gorphe P, Espitalier F, Blanchard D, Fakhry N, Saroul N et al (2019) Assessment of swallowing function after circumferential pharyngolaryngectomy. A multicenter study by the GETTEC group. Eur Ann Otorhinolaryngol Head Neck Dis 136(1):3–5

    Article  Google Scholar 

Download references

Funding

The present investigation has not received specific aid from public agencies, commercial or non-profit entities.

Author information

Authors and Affiliations

Authors

Contributions

All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by PS and JLL. The first draft of the manuscript was written by JLL and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to P. Sánchez.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Informed consent

Additional informed consent was obtained from all individual participants for whom identifying information is included in this article.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Llorente, J.L., Sánchez, P., López, F. et al. Closing of large pharyngostomes with free flaps and proposal of a new classification. Eur Arch Otorhinolaryngol 277, 3137–3144 (2020). https://doi.org/10.1007/s00405-020-06010-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00405-020-06010-x

Keywords

Navigation