Influence of olfactory dysfunction on the perception of food

Abstract

Purpose

Eating-related problems are among the most frequent issues in olfactory impairment, causing a noticeable loss of quality of life for some of the affected persons. To what extent olfactory dysfunction impacts on the sensory perception of food is less explored. The aim of the present study was to examine the impact of olfactory dysfunction on the perception of food aromas, as well as the perception of the “basic tastes” salty, sour, sweet, and bitter.

Methods

Eighty-nine participants were recruited for the prospective study. Group 1 consisted of thoroughly examined patients with olfactory dysfunction (n = 48, mean age = 60.0 years), group 2 consisted of people with normal olfactory function (n = 41, mean age = 50.4 years). First, olfactory and gustatory functions were assessed for all participants with the help of the “Sniffin’Sticks” battery and the “taste strips” test. Second, food odors were rated for their pleasantness, intensity, familiarity and desirability. Last, real food items were tasted orally and the intensity for basic taste qualities (sweet, bitter, salty, and sour) and pleasantness was rated. In addition, salivation was measured following exposure to the food odors.

Results

In comparison to controls, patients rated orthonasal food odors as less pleasant, intense, familiar, and less appetizing. “Taste strip” scores were significantly lower in patients (M = 9.56, SD = 2.76) as compared to controls (M = 10.88, SD = 1.89). In addition, ratings of food liking for chocolate and peanut were lower in patients compared to controls (chocolate: patients—M = 6.85, SD = 2.09, controls—M = 7.90, SD = 1.53; peanut: patients—M = 4.88, SD = 2.20, controls—M = 6.80, SD = 2.33). No significant differences were found regarding the comparison of the salivary flow rate in controls (M = 0.52 g/min, SD = 0.19) and patients (M = 0.50 SD = 0.17).

Conclusions

Changes in the perception of odors may change the perception of food with specific effects on food liking. Olfactory dysfunction affects gustatory function, indicating the central-nervous interaction between taste and smell. Still, olfactory dysfunction did not appear to affect patients’ salivary flow.

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Acknowledgements

The authors thank Han-Seok Seo, PhD for assisting in data acquisition. This research was supported by a grant from the Deutsche Forschungsgemeinschaft to TH (DFG HU411/18–1).

Funding

Source of financial support or funding: This research was supported by a grant from the Deutsche Forschungsgemeinschaft to TH (DFG HU411/18–1).

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Correspondence to T. Hummel.

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This research received financial support by the Deutsche Forschungsgemeinschaft to TH (DFG HU411/18–1). All other authors declare that they have no conflict of interest.

Research involving human participants

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study was approved by the Ethics committee of the Medical Faculty of the Technical University of Dresden(EK441102016). This article does not contain any studies with animals performed by any of the authors.

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Informed consent was obtained from all individual participants included in the study.

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Zang, Y., Han, P., Burghardt, S. et al. Influence of olfactory dysfunction on the perception of food. Eur Arch Otorhinolaryngol 276, 2811–2817 (2019). https://doi.org/10.1007/s00405-019-05558-7

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Keywords

  • Olfactory dysfunction
  • Smell
  • Eating
  • Taste
  • Flavor