The conclusion is reliable only based on three retrospective studies with limited patients?

  • Meng-Si Luo
  • Guan-Jiang HuangEmail author
Letter to the Editor


Author contributions

Dr. Meng-Si Luo drafted the letter, and Dr. Guan-Jiang Huang revised the letter.



Compliance with ethical standards

Conflict of interest

The authors declares that they have no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.


  1. 1.
    Saengthong P, Chaitusaney B, Hirunwiwatkul P, Charakorn N (2019) Adenotonsillectomy in children with syndromic craniosynostosis: a systematic review and meta-analysis. Eur Arch Otorhinolaryngol 276:1555–1560CrossRefGoogle Scholar
  2. 2.
    Higgins JPT, Green S (2011) Cochrane handbook for systematic reviews of interventions version 5.1.0 [updated March 2011]. In: The Cochrane Collaboration, 2011.
  3. 3.
    Li M, Tang Z (2015) Lowering blood pressure in patients with diabetes. JAMA 313:2183CrossRefGoogle Scholar
  4. 4.
    Lefebvre C, Eisinga A, McDonald S, Paul N (2008) Enhancing access to reports of randomized trials published world-wide—the contribution of EMBASE records to the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library. Emerg Themes Epidemiol 5:13CrossRefGoogle Scholar
  5. 5.
    Liberati A, Altman DG, Tetzlaff J et al (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ 339:b2700CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Anesthesiology, Zhongshan Hospital of Traditional Chinese MedicineAffiliated to Guangzhou University of Chinese MedicineZhongshanChina
  2. 2.Department of Otorhinolaryngology, The Second Affiliated Hospital, School of MedicineZhejiang UniversityHangzhouChina

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