Skip to main content
Log in

Olfactory dysfunction: properties of the Sniffin’ Sticks Screening 12 test and associations with quality of life

  • Rhinology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Purpose

The Sniffin’ Sticks Screening 12 test is a test of olfactory performance based on pen-like odor dispensing devices. The aims of this study were to analyze the performance of this test in a general population sample and to explore associations between olfactory dysfunction and quality of life.

Methods

A large community sample (n = 7267) completed the Sniffin’ Sticks Screening 12 test and several questionnaires measuring quality of life, anxiety, dispositional optimism, social support, and satisfaction with life.

Results

According to the criteria recommended by the test manufacturer, 5.1% of the participants were anosmic (score ≤ 6), 52.4% were dysosmic (7 ≤ score ≤ 10), and 42.5% were normosmic (score ≥ 11). While frequencies of correct identification differed between the 12 sticks, all sticks contributed positively to the test results. The associations between olfactory functioning and quality of life variables were negligible. In the multivariate analyses, none of the associations reached the 1% significance level.

Conclusions

While studies with patients in otorhinolaryngological clinics often report substantial detriments to their quality of life in relation to olfactory dysfunction, the present epidemiological study cannot confirm this association for the general population.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Hummel T, Kobal G, Gudziol H et al (2007) Normative data for the “Sniffin’ Sticks” including tests of odor identification, odor discrimination, and olfactory thresholds: An upgrade based on a group of more than 3000 subjects. Eur Arch Otorhinolaryngol 264(3):237–243. https://doi.org/10.1007/s00405-006-0173-0

    Article  PubMed  CAS  Google Scholar 

  2. Rumeau C, Nguyen DT, Jankowski R (2016) How to assess olfactory performance with the Sniffin’ Sticks test(®). Eur Ann Otorhinolaryngol Head Neck Dis 133(3):203–206. https://doi.org/10.1016/j.anorl.2015.08.004

    Article  PubMed  CAS  Google Scholar 

  3. Sorokowska A, Albrecht E, Haehner A et al (2015) Extended version of the “Sniffin’ Sticks” identification test: test-retest reliability and validity. J Neurosci Methods 243:111–114. https://doi.org/10.1016/j.jneumeth.2015.01.034

    Article  PubMed  CAS  Google Scholar 

  4. Lin S-H, Chu S-T, Yuan B-C et al (2009) Survey of the frequency of olfactory dysfunction in Taiwan. J Chin Med Assoc 72(2):68–71. https://doi.org/10.1016/S1726-4901(09)70025-5

    Article  PubMed  Google Scholar 

  5. Sorokowska A, Schriever VA, Gudziol V et al (2015) Changes of olfactory abilities in relation to age: Odor identification in more than 1400 people aged 4 to 80 years. Eur Arch Otorhinolarygol 272(8):1937–1944. https://doi.org/10.1007/s00405-014-3263-4

    Article  CAS  Google Scholar 

  6. Katotomichelakis M, Balatsouras D, Tripsianis G et al (2007) Normative values of olfactory function testing using the ‘sniffin’ sticks’. Laryngoscope 117(1):114–120. https://doi.org/10.1097/01.mlg.0000246518.79894.7e

    Article  PubMed  Google Scholar 

  7. Fjaeldstad A, Kjaergaard T, van Hartevelt TJ et al (2015) Olfactory screening: validation of Sniffin’ Sticks in Denmark. Clin Otolaryngol 40(6):545–550. https://doi.org/10.1111/coa.12405

    Article  PubMed  CAS  Google Scholar 

  8. Kohli P, Soler ZM, Nguyen SA et al (2016) The association between olfaction and depression: a systematic review. Chem Senses 41(6):479–486. https://doi.org/10.1093/chemse/bjw061

    Article  PubMed  PubMed Central  Google Scholar 

  9. Khil L, Rahe C, Wellmann J et al (2016) Association between major depressive disorder and odor identification impairment. J Affect Disord 203:332–338. https://doi.org/10.1016/j.jad.2016.06.022

    Article  PubMed  Google Scholar 

  10. Kollndorfer K, Reichert JL, Brückler B et al (2017) Self-esteem as an important factor in quality of life and depressive symptoms in anosmia: a pilot study. Clin Otolaryngol 42(6):1229–1234. https://doi.org/10.1111/coa.12855

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  11. Hummel T, Nordin S (2009) Olfactory disorders and their consequences for quality of life. Acta Oto-Laryngol 125(2):116–121. https://doi.org/10.1080/00016480410022787

    Article  Google Scholar 

  12. Croy I, Nordin S, Hummel T (2014) Olfactory disorders and quality of life—an updated review. Chem Senses 39(3):185–194. https://doi.org/10.1093/chemse/bjt072

    Article  PubMed  Google Scholar 

  13. Temmel AFP, Quint C, Schickinger-Fischer B et al (2002) Characteristics of olfactory disorders in relation to major causes of olfactory loss. Arch Otolaryngol Head Neck Surg 128(6):635. https://doi.org/10.1001/archotol.128.6.635

    Article  PubMed  Google Scholar 

  14. Tafalla M (2013) A world without the olfactory dimension. Anat Rec 296(9):1287–1296. https://doi.org/10.1002/ar.22734

    Article  Google Scholar 

  15. Neuland C, Bitter T, Marschner H et al (2011) Health-related and specific olfaction-related quality of life in patients with chronic functional anosmia or severe hyposmia. Laryngoscope 121(4):867–872. https://doi.org/10.1002/lary.21387

    Article  PubMed  Google Scholar 

  16. Smeets MAM, Veldhuizen MG, Galle S et al (2009) Sense of smell disorder and health-related quality of life. Rehabil Psychol 54(4):404–412. https://doi.org/10.1037/a0017502

    Article  PubMed  Google Scholar 

  17. Loeffler M, Engel C, Ahnert P et al (2015) The LIFE-Adult-Study: objectives and design of a population-based cohort study with 10,000 deeply phenotyped adults in Germany. BMC Public Health 15(1):691. https://doi.org/10.1186/s12889-015-1983-z

    Article  PubMed  PubMed Central  Google Scholar 

  18. Hummel T, Konnerth CG, Rosenheim K et al (2001) Screening of olfactory function with a 4-min odor identification test: reliability, normative data, and investigations in patients with olfactory loss. Ann Otol Rhinol Laryngol 110(10):976–981. https://doi.org/10.1177/000348940111001015

    Article  PubMed  CAS  Google Scholar 

  19. Ware JE, Kosinski M, Dewey JE et al (2001) How to score and interpret single-item health status measures: A manual for users of the SF-8™ Health Survey. QualityMetric Incorporated, Lincoln (RI)

    Google Scholar 

  20. Spitzer RL, Kroenke K, Williams JBW et al (2006) A brief measure for assessing generalized anxiety disorder - The GAD-7. Arch Int Med 166(10):1092–1097

    Article  Google Scholar 

  21. Scheier MF, Carver CS, Bridges MW (1994) Distinguishing optimism from neuroticism (and trait anxiety, self-mastery, and self-esteem)—a reevaluation of the life orientation test. J Pers Soc Psychol 67(6):1063–1078. https://doi.org/10.1037/0022-3514.67.6.1063

    Article  PubMed  CAS  Google Scholar 

  22. Berkman LF, Blumenthal J, Burg M et al (2003) Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the enhancing recovery in coronary heart disease patients (ENRICHD) randomized trial. JAMA 289(23):3106–3116. https://doi.org/10.1001/jama.289.23.3106

    Article  PubMed  Google Scholar 

  23. Diener E, Emmons RA, Larsen RJ et al (1985) The Satisfaction with life scale. J Personal Assess 49(1):71–75

    Article  CAS  Google Scholar 

  24. Lampert T, Kroll L, Mueters S et al (2013) Measurement of the socioeconomic status within the German Health Update 2009 (GEDA). Bundesgesundheitsblatt-Gesundheitsforschung-Gesundheitsschutz 56(1):131–143

    Article  PubMed  CAS  Google Scholar 

  25. Cronbach LJ (1951) Coefficient alpha and the internal structure of tests. Psychometrika 16:297–334

    Article  Google Scholar 

  26. Oleszkiewicz A, Taut M, Sorokowska A et al (2016) Development of the Arabic version of the “Sniffin’ Sticks” odor identification test. Eur Arch Otorhinolaryngol 273(5):1179–1184. https://doi.org/10.1007/s00405-015-3718-2

    Article  PubMed  Google Scholar 

  27. Croy I, Buschhüter D, Seo H-S et al (2010) Individual significance of olfaction: development of a questionnaire. Eur Arch Otorhinolarygol 267(1):67–71. https://doi.org/10.1007/s00405-009-1054-0

    Article  Google Scholar 

  28. Simopoulos E, Katotomichelakis M, Gouveris H et al (2012) Olfaction-associated quality of life in chronic rhinosinusitis: adaptation and validation of an olfaction-specific questionnaire. Laryngoscope 122(7):1450–1454. https://doi.org/10.1002/lary.23349

    Article  PubMed  Google Scholar 

  29. Masala C, Saba L, Cecchini MP et al (2018) Olfactory function and age: A Sniffin’ Sticks Extended Test study performed in Sardinia. Chem Percept 11(1):19–26. https://doi.org/10.1007/s12078-017-9233-7

    Article  Google Scholar 

  30. Yuan BC, Lee PL, Lee YL et al (2010) Investigation of the Sniffin’ Sticks Olfactory Test in Taiwan and comparison with different continents. J Chin Med Assoc 73(9):483–486. https://doi.org/10.1016/S1726-4901(10)70103-9

    Article  PubMed  Google Scholar 

Download references

Funding

This publication was supported by LIFE—Leipzig Research Centre for Civilization Diseases, an organizational unit affiliated to the Medical faculty of the University of Leipzig. LIFE was funded by means of the European Union, by the European Regional Development Fund (ERDF) and by funds of the Free State of Saxony within the excellence initiative (project numbers 713-241202, 14505/2470, 14575/2470).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Andreas Hinz.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

The study was approved by the Ethics Committee of the University of Leipzig, Germany, and has been performed in accordance with the ethical standards as laid down in the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Hinz, A., Luck, T., Riedel-Heller, S.G. et al. Olfactory dysfunction: properties of the Sniffin’ Sticks Screening 12 test and associations with quality of life. Eur Arch Otorhinolaryngol 276, 389–395 (2019). https://doi.org/10.1007/s00405-018-5210-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00405-018-5210-2

Keywords

Navigation