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The effect of “xanthan gum-based fluid thickener” on hydration, swallowing functions and nutritional status in total maxillectomy patients

  • Rhinology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Purpose

Swallowing functions are affected after total maxillectomy operations and adjuvant chemoradiotherapy. The purpose of our study is to assess the role of xanthan gum based thickening agents on swallowing and hydration of maxillectomy patients on a randomized controlled fashion.

Methods

12 of the 22 patients diagnosed with maxillary carcinoma and planned to undergo total maxillectomy was identified as study group and 10 of them were identified as control group. The study group used “xantham based liquid thickener” for liquid foods up to 3 months postoperatively and the control group did not use. Dysphagia-related quality of life, bioimpedance analysis, EAT-10 scores, swallowing functions were evaluated both preoperative and postoperative period.

Results

The mean age of the study group was 56 ± 9.87, and 41.6% were women. The mean age of control group was 60 ± 15.63, and 50% were women. Postoperative EAT-10 scores were statistically significant higher than preoperative scores in both groups (p < 0.05). In both of the study and control groups, a statistically significant reduction in dysphagia related quality of life was detected postoperatively (p < 0.05). Intracellular water, extracellular water and total body water detected statistically significant higher in study group at postoperative month three.

Conclusion

Swallowing functions are affected due to total maxillectomy and radiotherapy. With this study, it has been shown that, total maxillectomy and radiotherapy reduce dysphagia-related quality of life. Swallowing dysfunction and dehydration has been shown to affect total maxillectomy patients. Using of ‘xanthan gum-based fluid thickener’ helps to maintain intracellular water, extracellular water, and total body water.

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References

  1. Vickery LE, Latchford G, Hewison J, Bellew M, Feber T (2003) The impact of head and neck cancer and facial disfigurement on the quality of life of patients and their partners. Head Neck 25:289–296

    Article  Google Scholar 

  2. Flint PW, Haughey BH, Niparko JK, Richardson MA, Lund VJ, Robbins KT, Lesperance MM, Thomas JR (2015) Cummings otolaryngology–head & neck surgery, 6th edn. Elsevier, Saunders, pp 1622–1624

    Google Scholar 

  3. Said MM, Otomaru T, Yeerken Y, Taniguchi H (2017) Masticatory function and oral health-related quality of life in patients after partial maxillectomies with closed or open defects. J Prosthet Dent 118(1):108–112

    Article  Google Scholar 

  4. Kamiyanagi A, Sumita Y, Ino S, Chikai M, Nakane A, Tohara H, Minakuchi S, Seki Y, Endo H, Taniguchi H (2018) Evaluation of swallowing ability using swallowing sounds in maxillectomy patients. J Oral Rehabil 45(2):126–131

    Article  CAS  Google Scholar 

  5. Sreeraj R, Krishnan V, Thankappan K (2017) Comparison of masticatory and swallowing functional outcomes in surgically and prosthetically rehabilitated maxillectomy patients. Int J Prosthodont 30(6):573–576

    Article  CAS  Google Scholar 

  6. Jansma J, Vissink A, Bouma J, Vermey A, Panders AK, Gravenmade EJ (1992) A survey of prevention and treatment regimens for oral sequelae resulting from head and neck radiotherapy used in Dutch radiotherapy institutes. Int J Radiat Oncol Biol Phys 24(2):359–367

    Article  CAS  Google Scholar 

  7. Jansma J, Vissink A, Spijkervet FK et al (1992) Protocol for the prevention and treatment of oral sequelae resulting from head and neck radiotherapy. Cancer 70:2171–2180

    Article  CAS  Google Scholar 

  8. Nguyen NP, Sallah S, Karlsson U et al (2002) Combined chemotherapy and radiation therapy for head and neck malignancies: quality of life issues. Cancer 94:1131–1141

    Article  Google Scholar 

  9. Pauloski BR (2008) Rehabilitation of dysphagia following head and neck cancer. Phys Med Rehabil Clin N Am 19(4):889–928

    Article  Google Scholar 

  10. Jadcherla SR, McCullough GH, Daniels SK, Van Daele DJ, Dua K, Lazarus C, Shaker R (2017) The dysphagia research society accelerating a priority research agenda. Dysphagia 32:11–14

    Article  Google Scholar 

  11. Curtis JA, Laus J, Yung KC, Courey MS (2016) Static endoscopic evaluation of swallowing: transoral endoscopy during clinical swallow evaluations. Laryngoscope 126(10):2291–2294

    Article  Google Scholar 

  12. Demirci C, Aşcı G, Demirci MS, Özkahya M, Töz H, Duman S, Sipahi S, Erten S, Tanrısev M, Ok E (2016) Impedance ratio: a novel marker and a powerful predictor of mortality in hemodialysis patients. Int Urol Nephrol 48(7):1155–1162

    Article  CAS  Google Scholar 

  13. Schneditz D (2006) The arrow of bioimpedance. Kidney Int 69:1492–1493

    Article  CAS  Google Scholar 

  14. Kräemer M, Rode C, Wizemann V (2006) Detection limit of methods to assess fluid status in dialysis patients. Kidney Int 69:1609–1620

    Article  Google Scholar 

  15. Kotanko P, Levin NW, Zhu F (2008) Current state of bioimpedance technologies in dialysis. Nephrol Dial Transplant 23(3):808–812

    Article  Google Scholar 

  16. Park J, Yang WS, Kim SB, Park SK, Lee SK, Park JS, Chang JW (2009) Usefulness of segmental bioimpedance ratio to determine dry body weight in new hemodialysis patients: a pilot study. Am J Nephrol 29(1):25–30

    Article  Google Scholar 

  17. Gangji AS, Brimble KS, Margetts PJ (2009) Association between markers of inflammation, fibrosis and hypervolemia in peritoneal dialysis patients. Blood Purif 28(4):354–358

    Article  CAS  Google Scholar 

  18. Rofes L, Arreola V, Mukherjee R, Swanson J, Clav P (2014) Effects of a xanthan gum-based thickener on the swallowing function of patients with dysphagia. Aliment Pharmacol Ther 39(10):1169–1179

    Article  CAS  Google Scholar 

  19. Crary MA, Carnaby-Mann GD, Groher ME (2005) Initial psychometric assessment of a functional oral intake scale for dysphagia in stroke patients. Arch Phys Med Rehabil 86:1516–1520

    Article  Google Scholar 

  20. Salassa JR (1999) A Functional Outcome Swallowing Scale for Staging Oropharyngeal Dysphagia. Department of Otorhinolaryngology, Mayo Clinic, Jacksonville, Fl, USA. Dig Dis 17(4):230–234. https://doi.org/10.1159/000016941

    Article  CAS  PubMed  Google Scholar 

  21. Chen AY, Frankowski R, Bishop-Leone J, Hebert T, Leyk S, Lewin J, Goepfert H (2001) The development and validation of a dysphagia-specific quality-of-life questionnaire for patients with head and neck cancer: the M. D. Anderson dysphagia inventory. Arch Otolaryngol Head Neck Surg 127(7):870–876

    CAS  PubMed  Google Scholar 

  22. Cheney DM, Siddiqui MT, Litts JK, Kuhn MA, Belafsky PC (2015) The ability of the 10-item eating assessment tool (EAT-10) to predict aspiration risk in persons with dysphagia. Ann Otol Rhinol Laryngol 124(5):351–354

    Article  Google Scholar 

  23. Rofes L, Arreola V, Mukherjee R, Clavé P (2014) Sensitivity and specificity of the Eating Assessment Tool and the Volume-Viscosity Swallow Test for clinical evaluation of oropharyngeal dysphagia. Neurogastroenterol Motil 26(9):1256–1265

    Article  CAS  Google Scholar 

  24. Giridhar VU (2016) Role of nutrition in oral and maxillofacial surgery patients. Natl J Maxillofac Surg 7(1):3–9

    Article  Google Scholar 

  25. Zhu F, Wystrychowski G, Kitzler T, Thijssen S, Kotanko P, Levin NW (2006) Application of bioimpedance techniques to peritoneal dialysis. Contrib Nephrol 150:119–128

    Article  CAS  Google Scholar 

  26. Cichero JA (2013) Thickening agents used for dysphagia management: effect on bioavailability of water, medication and feelings of satiety. Nutr J 12:54

    Article  Google Scholar 

  27. Zhou YL, Liu J, Sun F, Ma LJ, Han B, Shen Y, Cui TG (2010) Calf bioimpedance ratio improves dry weight assessment and blood pressure control in hemodialysis patients. Am J Nephrol 32(2):109–116

    Article  Google Scholar 

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Funding

This research received no specific grant from any funding agency.

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Authors and Affiliations

  1. Otorhinolaryngology Department, Ege University School of Medicine, Izmir, Turkey

    Baha Sezgin, Duygu Durusoy, Kerem Ozturk, Isa Kaya & Sercan Gode

  2. Nephrology Department, Internal Medicine, Ege University School of Medicine, Izmir, Turkey

    Meltem Sezis Demirci

  3. Physical Medicine and Rehabilitation Department, Ege University School of Medicine, Izmir, Turkey

    Sibel Eyigor

Authors
  1. Baha Sezgin
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  2. Duygu Durusoy
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  3. Meltem Sezis Demirci
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  4. Kerem Ozturk
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  5. Isa Kaya
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  6. Sibel Eyigor
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  7. Sercan Gode
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Correspondence to Baha Sezgin.

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Sezgin, B., Durusoy, D., Demirci, M.S. et al. The effect of “xanthan gum-based fluid thickener” on hydration, swallowing functions and nutritional status in total maxillectomy patients. Eur Arch Otorhinolaryngol 275, 2997–3005 (2018). https://doi.org/10.1007/s00405-018-5167-1

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  • DOI: https://doi.org/10.1007/s00405-018-5167-1

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