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Efficacy and safety of preoperative internal maxillary arterial embolization with gelfoam for nasopharyngeal angiofibroma

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Abstract

Purpose

To investigate the efficacy and safety of preoperative internal maxillary arterial embolization with gelfoam particles in patients with nasopharyngeal angiofibroma.

Materials and methods

We retrospectively reviewed a total of 27 consecutive patients with pathologically confirmed nasopharyngeal angiofibroma from August 2006 to September 2018. Of the 27 enrolled patients, 10 patients received surgical excision alone; 17 patients received preoperative internal maxillary arterial embolization followed by surgical excision. Embolic agents were gelfoam particles.

Results

The mean volume of intro-operative blood loss was 385.3 ml in patients with preoperative arterial embolization, which was significantly lower than 1215.0 ml in the patients without preoperative arterial embolization (P < 0.001). The mean surgical time was shorter in patients with preoperative arterial embolization than in the patient without preoperative arterial embolization, but the difference had no statistical significance (205.0 vs 264.5 min, P = 0.064). Neurological complications such as facial palsy or vision loss or hemiplegia were not observed in patients with preoperative arterial embolization.

Conclusion

Internal maxillary artery embolization with gelfoam particles suffices to provide an effective and safe adjuvant procedure for surgical excision of nasopharyngeal angiofibroma.

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Authors and Affiliations

  1. Department of Interventional Radiology and Vascular Surgery, Peking University First Hospital, Beijing, 100034, People’s Republic of China

    Renguang Pei, Min Yang, Jian Wang, Xiaoqiang Tong & Yinghua Zou

  2. Department of Interventional Therapy, Yijishan Hospital of Wannan Medical College, Wuhu, People’s Republic of China

    Guoxiang Wang

Authors
  1. Renguang Pei
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  2. Min Yang
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  3. Jian Wang
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  4. Xiaoqiang Tong
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  5. Guoxiang Wang
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  6. Yinghua Zou
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Correspondence to Yinghua Zou.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. This article does not contain any studies with animals performed by any of the authors.

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Pei, R., Yang, M., Wang, J. et al. Efficacy and safety of preoperative internal maxillary arterial embolization with gelfoam for nasopharyngeal angiofibroma. Eur Arch Otorhinolaryngol 276, 865–869 (2019). https://doi.org/10.1007/s00405-018-05276-6

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  • DOI: https://doi.org/10.1007/s00405-018-05276-6

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