Abstract
Allergic rhinitis is an inflammatory disease that develops through immunoglobulin E in the rhino-ocular mucosa due to allergy. The main symptoms are runny nose, nasal congestion, sneezing and itchy nose. This study was designed to investigate the effect of allergic rhinitis on choroidal thickness. This study was planned as a case-control study. This study performed in a tertiary referral center. The study included 61 patients with allergic rhinitis and 35 healthy subjects. Patients in both groups underwent skin prick test. In allergic rhinitis patients and healthy persons; subfoveal, temporal and nasal choroidal thickness measurement was performed. The choroidal thicknesses were measured without pupil dilation using the Spectralis Optical Coherence Tomography. In the subfoveal and temporal region, choroidal tissue was followed up significantly thicker in allergic rhinitis patients statistically compared to healthy persons (p = 0.031, p = 0.049). However, no significant difference was followed up between the nasal choroidal thickness measurements statistically (p = 0.54). Runny nose (67.2%), sneeze (65.5%), stuffiness (62.2%), itching of the nose (40.9%), and nasal discharge (21.3%) complaints were observed significantly higher in the group having allergic rhinitis. The effect of allergic rhinitis on choroidal thickness were assessed and compared with the control group. Our study revealed that there was significant association between increased choroidal thickness and allergic rhinitis. Allergic sensitivity may play an important role in increased choroidal thickness.
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Abbreviations
- AR:
-
Allergic rhinitis
- EDI-OCT:
-
Enhanced depth imaging optical coherence tomography
- GAG:
-
Glycosaminoglycan
- IgE:
-
Immunoglobulin E
- NCSS:
-
Number Cruncher Statistical System
- OCT:
-
Optical Coherence Tomography
- PASS:
-
Power Analysis and Sample Size
- VKH:
-
Vogt-Koyanagi-Harada
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Yenigun, A., Elbay, A., Dogan, R. et al. The effect of allergic rhinitis with positive skin prick test on choroidal thickness. Eur Arch Otorhinolaryngol 274, 2477–2481 (2017). https://doi.org/10.1007/s00405-017-4513-z
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DOI: https://doi.org/10.1007/s00405-017-4513-z