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Does adenoid hypertrophy affect disease severity in children with allergic rhinitis?

  • Rhinology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

A Letter to the Editor to this article was published on 08 September 2017

Abstract

Our study aims to evaluate the presence of adenoid hypertrophy (AH) in children with allergic rhinitis (AR) and the association of AH disease severity and clinical laboratory finding from retrospective, cross-sectional, and nonrandomized trial. The study included 566 children being treated and followed up for allergic rhinitis. Skin prick test for the same allergens was performed for all patients. Adenoid tissue was analyzed by an ENT specialist and the diagnosis was confirmed based on the patient history, endoscopic physical examination and radiology. Adenoid hypertrophy was detected in 118 (21.2 %) of the children with AR. Children with and without AH did not differ statistically and significantly by gender, age, presence of atopy in the family, exposure to smoke (p > 0.05). Comparison of the groups for AR duration demonstrated significantly higher frequency of persistent rhinitis in patients with AH (p < 0.05). Of the AR patients with AH, 90 (76.3 %) had moderate-severe rhinitis and 274 (62.6 %) AR patients without AH had moderate-severe rhinitis (p = 0.005). Itchy nose was more frequent in AR patients without AH, and nasal congestion was more common in AR patients with AH (p = 0.017 and p = 0.001, respectively). The presence of asthma was more common among AR patients without AH (p = 0.037). Intergroup comparisons for presence of atopic dermatitis, the percentage of eosinophil, serum IgE levels, the number of positive sensitivity, polysensitization, sensitivity to house dust mite, cockroach, pollens and dander yielded no significant difference (p > 0.05). On the other hand, sensitivity to Alternaria alternata was significantly more frequent in AR patients with AH (p = 0.032). The presence of AH increased the severity of the disease and prolongs disease duration. There was a negative relationship between AH and asthma in children with AR. AH is more common among children with mold sensitivity. AH should be considered and investigated particularly in non-asthmatic children with pronounced nasal congestion and A. alternata sensitivity.

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Authors and Affiliations

  1. Department of Pediatrics, Zeynep Kamil Woman and Children’s Diseases Training and Research Hospital, Burhanettin Ustunel Cad. No.10 Uskudar, Istanbul, Turkey

    Mahmut Dogru

  2. Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Istanbul Medipol University, Istanbul, Turkey

    Muhammed Fatih Evcimik

  3. Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Health Sciences, Bezmi Alem University, Istanbul, Turkey

    Omer Faruk Calim

Authors
  1. Mahmut Dogru
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  2. Muhammed Fatih Evcimik
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  3. Omer Faruk Calim
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Corresponding author

Correspondence to Mahmut Dogru.

Ethics declarations

The study was approved by the Istanbul Medipol University Ethics committee and adhered to the principles of Helsinki Declaration. An oral consent was obtained from all subjects and/or their parents.

Funding

This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors. This study was funded by authors.

Conflict of interest

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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Dogru, M., Evcimik, M.F. & Calim, O.F. Does adenoid hypertrophy affect disease severity in children with allergic rhinitis?. Eur Arch Otorhinolaryngol 274, 209–213 (2017). https://doi.org/10.1007/s00405-016-4196-x

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  • DOI: https://doi.org/10.1007/s00405-016-4196-x

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