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Immunotherapy in all aspects

European Archives of Oto-Rhino-Laryngology volume 273, pages 1347–1355 (2016)Cite this article

Abstract

Allergen immunotherapy is a form of long-term treatment that decreases symptoms for many people with allergic rhinitis, allergic asthma, conjunctivitis (eye allergy) or stinging insect allergy. In this review, we presented the important topics in immunotherapy. The important aspects of immunotherapy are considered to be “Immunologıcal responses to immunotherapy”; “The principal types of immunotherapy”; “Effectiveness”; “Indications”; “Contraindications”; “Allergen immunotherapy in children”; “Safety”; and “Anaphylactic reactions after immunotherapy”. The principal types of immunotherapy are subcutaneous immunotherapy (SCIT) and sublingual immunotherapy. Both of them can be used in indicated cases. When using SCIT, physicians must be more careful because of reported rare fatal cases. The risks and benefits of continuing allergen immunotherapy in patients who have experienced severe systemic reactions should be carefully considered.

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Acknowledgments

“With exception of data collection, preparation of this paper including design and planning was supported by Continuous Education and Scientific Research Association”.

Conflict of interest

The authors declare that there is no conflict of interest.

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Affiliations

  1. Okmeydanı Training and Research Hospital, ENT Clinics, Istanbul, Turkey

    Deniz Hanci

  2. Bayındır Göztepe Hospital, ENT Clinics, Istanbul, Turkey

    Ethem Şahin

  3. ENT Department, Medical Faculty, Kırıkkale University, Kirikkale, Turkey

    Nuray Bayar Muluk

  4. ENT Department, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey

    Cemal Cingi

  5. Birlik Mahallesi, Zirvekent 2. Etap Sitesi, C-3 blok, No: 62/43, 06610, Çankaya, Ankara, Turkey

    Nuray Bayar Muluk

Authors
  1. Deniz Hanci
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  2. Ethem Şahin
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  3. Nuray Bayar Muluk
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  4. Cemal Cingi
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Corresponding author

Correspondence to Nuray Bayar Muluk.

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Hanci, D., Şahin, E., Muluk, N.B. et al. Immunotherapy in all aspects. Eur Arch Otorhinolaryngol 273, 1347–1355 (2016). https://doi.org/10.1007/s00405-015-3553-5

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  • DOI: https://doi.org/10.1007/s00405-015-3553-5

Keywords

  • Immunotherapy
  • Subcutaneous immunotherapy (SCIT)
  • Sublingual immunotherapy (SLIT)
  • Effectiveness
  • Safety